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3bd3

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(New page: 200px {{Structure |PDB= 3bd3 |SIZE=350|CAPTION= <scene name='initialview01'>3bd3</scene>, resolution 1.6&Aring; |SITE= <scene name='pdbsite=AC1:Btb+Binding+Site+F...)
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[[Image:3bd3.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of single domain VL of an anti-DNA binding antibody 3D8 scFv and its active site revealed by complex structures of a small molecule and metals==
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|PDB= 3bd3 |SIZE=350|CAPTION= <scene name='initialview01'>3bd3</scene>, resolution 1.6&Aring;
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<StructureSection load='3bd3' size='340' side='right'caption='[[3bd3]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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|SITE= <scene name='pdbsite=AC1:Btb+Binding+Site+For+Residue+B+1'>AC1</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>
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<table><tr><td colspan='2'>[[3bd3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BD3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BD3 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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|GENE= 3d8 vl ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00099 IGv], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam07686 V-set]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bd3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bd3 OCA], [https://pdbe.org/3bd3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bd3 RCSB], [https://www.ebi.ac.uk/pdbsum/3bd3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bd3 ProSAT]</span></td></tr>
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|RELATEDENTRY=[[3bd4|3BD4]], [[3bd5|3BD5]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bd3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bd3 OCA], [http://www.ebi.ac.uk/pdbsum/3bd3 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3bd3 RCSB]</span>
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== Evolutionary Conservation ==
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}}
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bd/3bd3_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bd3 ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of single domain VL of an anti-DNA binding antibody 3D8 scFv and its active site revealed by complex structures of a small molecule and metals'''
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==See Also==
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*[[Antibody 3D structures|Antibody 3D structures]]
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*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
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==About this Structure==
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*[[3D structures of non-human antibody|3D structures of non-human antibody]]
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3BD3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BD3 OCA].
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__TOC__
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</StructureSection>
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==Reference==
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[[Category: Large Structures]]
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Crystal structure of single-domain VL of an anti-DNA binding antibody 3D8 scFv and its active site revealed by complex structures of a small molecule and metals., Park SY, Lee WR, Lee SC, Kwon MH, Kim YS, Kim JS, Proteins. 2008 Mar 12;. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18338383 18338383]
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Single protein]]
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[[Category: Kim JS]]
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[[Category: Kim, J S.]]
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[[Category: Park SK]]
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[[Category: Park, S K.]]
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[[Category: 3d8]]
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[[Category: anti-dna]]
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[[Category: catalytic antibody]]
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[[Category: immune system]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 2 11:59:12 2008''
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Current revision

Crystal structure of single domain VL of an anti-DNA binding antibody 3D8 scFv and its active site revealed by complex structures of a small molecule and metals

PDB ID 3bd3

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