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3bkm

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==Structure of anti-amyloid-beta Fab WO2 (Form A, P212121)==
==Structure of anti-amyloid-beta Fab WO2 (Form A, P212121)==
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<StructureSection load='3bkm' size='340' side='right' caption='[[3bkm]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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<StructureSection load='3bkm' size='340' side='right'caption='[[3bkm]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3bkm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BKM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BKM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3bkm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BKM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BKM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3bae|3bae]], [[3bkc|3bkc]], [[3bkj|3bkj]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bkm OCA], [http://pdbe.org/3bkm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bkm RCSB], [http://www.ebi.ac.uk/pdbsum/3bkm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3bkm ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bkm OCA], [https://pdbe.org/3bkm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bkm RCSB], [https://www.ebi.ac.uk/pdbsum/3bkm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bkm ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A2NHM3_MOUSE A2NHM3_MOUSE]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bk/3bkm_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bk/3bkm_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[3D structures of antibody|3D structures of antibody]]
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*[[Antibody 3D structures|Antibody 3D structures]]
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*[[Sandbox 20009|Sandbox 20009]]
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*[[3D structures of non-human antibody|3D structures of non-human antibody]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Bageley, C J]]
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[[Category: Bageley CJ]]
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[[Category: Barnham, K J]]
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[[Category: Barnham KJ]]
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[[Category: Beyreuther, K]]
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[[Category: Beyreuther K]]
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[[Category: Cappai, R]]
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[[Category: Cappai R]]
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[[Category: Crespi, G A]]
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[[Category: Crespi GA]]
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[[Category: Fodero-Tavoletti, M]]
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[[Category: Fodero-Tavoletti M]]
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[[Category: Galatis, D]]
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[[Category: Galatis D]]
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[[Category: Masters, C L]]
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[[Category: Masters CL]]
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[[Category: McKinstry, W J]]
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[[Category: McKinstry WJ]]
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[[Category: Miles, L A]]
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[[Category: Miles LA]]
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[[Category: Parker, M W]]
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[[Category: Parker MW]]
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[[Category: Wun, K S]]
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[[Category: Wun KS]]
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[[Category: Abeta]]
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[[Category: Alzheimer's disease]]
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[[Category: Amyloid beta peptide]]
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[[Category: App]]
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[[Category: Fab]]
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[[Category: Immune system]]
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[[Category: Immunotherapy]]
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[[Category: Wo2]]
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Current revision

Structure of anti-amyloid-beta Fab WO2 (Form A, P212121)

PDB ID 3bkm

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