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3eo0

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==Structure of the Transforming Growth Factor-Beta Neutralizing Antibody GC-1008==
==Structure of the Transforming Growth Factor-Beta Neutralizing Antibody GC-1008==
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<StructureSection load='3eo0' size='340' side='right' caption='[[3eo0]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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<StructureSection load='3eo0' size='340' side='right'caption='[[3eo0]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3eo0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EO0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EO0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3eo0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EO0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EO0 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3eo1|3eo1]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3eo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eo0 OCA], [http://pdbe.org/3eo0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3eo0 RCSB], [http://www.ebi.ac.uk/pdbsum/3eo0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3eo0 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3eo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eo0 OCA], [https://pdbe.org/3eo0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3eo0 RCSB], [https://www.ebi.ac.uk/pdbsum/3eo0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3eo0 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q6PYX1_HUMAN Q6PYX1_HUMAN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eo/3eo0_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eo/3eo0_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[3D structures of antibody|3D structures of antibody]]
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*[[Antibody 3D structures|Antibody 3D structures]]
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*[[Sandbox 20009|Sandbox 20009]]
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*[[3D structures of non-human antibody|3D structures of non-human antibody]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Gruetter, C]]
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[[Category: Mus musculus]]
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[[Category: Gruetter, M G]]
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[[Category: Gruetter C]]
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[[Category: Cytokine neutralizing antibody]]
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[[Category: Gruetter MG]]
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[[Category: Fab fragment]]
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[[Category: Immune system]]
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Current revision

Structure of the Transforming Growth Factor-Beta Neutralizing Antibody GC-1008

PDB ID 3eo0

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