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3eu1

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==Crystal Structure determination of goat hemoglobin (Capra hircus) at 3 angstrom resolution==
==Crystal Structure determination of goat hemoglobin (Capra hircus) at 3 angstrom resolution==
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<StructureSection load='3eu1' size='340' side='right' caption='[[3eu1]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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<StructureSection load='3eu1' size='340' side='right'caption='[[3eu1]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3eu1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EU1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EU1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3eu1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EU1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EU1 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2qu0|2qu0]], [[2ri4|2ri4]], [[3d1a|3d1a]], [[3cy5|3cy5]], [[3d4x|3d4x]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3eu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eu1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3eu1 RCSB], [http://www.ebi.ac.uk/pdbsum/3eu1 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3eu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eu1 OCA], [https://pdbe.org/3eu1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3eu1 RCSB], [https://www.ebi.ac.uk/pdbsum/3eu1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3eu1 ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HBA1_CAPHI HBA1_CAPHI] Involved in oxygen transport from the lung to the various peripheral tissues. Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1. Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.[UniProtKB:P01946]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eu/3eu1_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eu/3eu1_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3eu1 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3eu1" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Capra hircus]]
[[Category: Capra hircus]]
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[[Category: Balasubramanian, M.]]
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[[Category: Large Structures]]
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[[Category: Moorthy, Pon Sathya.]]
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[[Category: Balasubramanian M]]
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[[Category: Neelagandan, K.]]
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[[Category: Neelagandan K]]
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[[Category: Ponnuswamy, M N.]]
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[[Category: Ponnuswamy MN]]
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[[Category: 3-diphospho glycerate]]
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[[Category: Sathya Moorthy P]]
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[[Category: Allosteric mechanism]]
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[[Category: Capra hircus]]
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[[Category: Hemoglobin]]
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[[Category: Low oxygen affinity]]
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[[Category: Oxygen storage]]
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[[Category: Oxygen transport]]
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Current revision

Crystal Structure determination of goat hemoglobin (Capra hircus) at 3 angstrom resolution

PDB ID 3eu1

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