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3f8n

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Current revision (15:28, 1 November 2023) (edit) (undo)
 
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<StructureSection load='3f8n' size='340' side='right'caption='[[3f8n]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
<StructureSection load='3f8n' size='340' side='right'caption='[[3f8n]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3f8n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F8N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F8N FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3f8n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F8N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F8N FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.15&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2fe3|2fe3]], [[2rgv|2rgv]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">perR ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f8n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f8n OCA], [https://pdbe.org/3f8n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f8n RCSB], [https://www.ebi.ac.uk/pdbsum/3f8n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f8n ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f8n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f8n OCA], [https://pdbe.org/3f8n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f8n RCSB], [https://www.ebi.ac.uk/pdbsum/3f8n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f8n ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PERR_BACSU PERR_BACSU]] Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA, ahpC, ahpF, the heme biosynthesis operon (hemAXCDBL), fur, perR, zosA and mrgA.
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[https://www.uniprot.org/uniprot/PERR_BACSU PERR_BACSU] Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA, ahpC, ahpF, the heme biosynthesis operon (hemAXCDBL), fur, perR, zosA and mrgA.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Vibrio subtilis ehrenberg 1835]]
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[[Category: Bacillus subtilis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Duarte, V]]
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[[Category: Duarte V]]
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[[Category: Ferrer, J L]]
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[[Category: Ferrer J-L]]
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[[Category: Jacquamet, L]]
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[[Category: Jacquamet L]]
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[[Category: Latour, J M]]
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[[Category: Latour J-M]]
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[[Category: Traore, D A.K]]
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[[Category: Traore DAK]]
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[[Category: Cytoplasm]]
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[[Category: Dna binding protein]]
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[[Category: Dna-binding]]
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[[Category: Helix-turn-helix]]
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[[Category: Manganese]]
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[[Category: Oxidation]]
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[[Category: Repressor]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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[[Category: Zinc]]
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Current revision

Crystal structure of PerR-Zn-Mn

PDB ID 3f8n

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