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3i1f

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==Gamma-subunit of the translation initiation factor 2 from S. solfataricus in complex with Gpp(CH2)p==
==Gamma-subunit of the translation initiation factor 2 from S. solfataricus in complex with Gpp(CH2)p==
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<StructureSection load='3i1f' size='340' side='right' caption='[[3i1f]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='3i1f' size='340' side='right'caption='[[3i1f]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3i1f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I1F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3I1F FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3i1f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I1F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I1F FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GCP:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>GCP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2plf|2plf]], [[2pmd|2pmd]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GCP:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>GCP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">eif2g ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i1f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i1f OCA], [https://pdbe.org/3i1f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i1f RCSB], [https://www.ebi.ac.uk/pdbsum/3i1f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i1f ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i1f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i1f OCA], [http://pdbe.org/3i1f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3i1f RCSB], [http://www.ebi.ac.uk/pdbsum/3i1f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3i1f ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IF2G_SULSO IF2G_SULSO]] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (By similarity).
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[https://www.uniprot.org/uniprot/IF2G_SACS2 IF2G_SACS2] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.[HAMAP-Rule:MF_00119]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i1/3i1f_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i1/3i1f_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 35091]]
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[[Category: Large Structures]]
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[[Category: Blaesi, U]]
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[[Category: Saccharolobus solfataricus]]
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[[Category: Garber, M B]]
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[[Category: Blaesi U]]
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[[Category: Nikonov, O S]]
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[[Category: Garber MB]]
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[[Category: Nikonov, S V]]
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[[Category: Nikonov OS]]
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[[Category: Nikulin, A D]]
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[[Category: Nikonov SV]]
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[[Category: Stolboushkina, E A]]
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[[Category: Nikulin AD]]
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[[Category: Aif2]]
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[[Category: Stolboushkina EA]]
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[[Category: Gdpcp]]
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[[Category: Gtp-binding]]
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[[Category: Initiation factor]]
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[[Category: Initiation factor 2 gamma subunit]]
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[[Category: Initiation of the translation]]
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[[Category: Mrna binding]]
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[[Category: Nucleotide binding]]
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[[Category: Nucleotide-binding]]
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[[Category: Protein biosynthesis]]
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[[Category: Translation]]
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Current revision

Gamma-subunit of the translation initiation factor 2 from S. solfataricus in complex with Gpp(CH2)p

PDB ID 3i1f

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