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3jti

From Proteopedia

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{{Seed}}
 
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[[Image:3jti.jpg|left|200px]]
 
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==Crystal structure of the complex formed between Phospholipase A2 with beta-amyloid fragment, Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met at 1.8 A resolution==
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The line below this paragraph, containing "STRUCTURE_3jti", creates the "Structure Box" on the page.
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<StructureSection load='3jti' size='340' side='right'caption='[[3jti]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3jti]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Naja_sagittifera Naja sagittifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JTI FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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{{STRUCTURE_3jti| PDB=3jti | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jti FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jti OCA], [https://pdbe.org/3jti PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jti RCSB], [https://www.ebi.ac.uk/pdbsum/3jti PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jti ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PA2A3_NAJSG PA2A3_NAJSG] PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jt/3jti_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3jti ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of the complex formed between Phospholipase A2 with beta-amyloid fragment, Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met at 1.8 A resolution===
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==See Also==
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*[[Amyloid precursor protein 3D structures|Amyloid precursor protein 3D structures]]
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*[[Phospholipase A2 3D structures|Phospholipase A2 3D structures]]
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==About this Structure==
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__TOC__
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3JTI is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Naja_sagittifera Naja sagittifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTI OCA].
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
[[Category: Naja sagittifera]]
[[Category: Naja sagittifera]]
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[[Category: Bhushan, A.]]
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[[Category: Bhushan A]]
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[[Category: Kaur, P.]]
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[[Category: Kaur P]]
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[[Category: Mirza, Z.]]
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[[Category: Mirza Z]]
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[[Category: Pandey, N.]]
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[[Category: Pandey N]]
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[[Category: Sharma, S.]]
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[[Category: Sharma S]]
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[[Category: Singh, N.]]
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[[Category: Singh N]]
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[[Category: Singh, T P.]]
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[[Category: Singh TP]]
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[[Category: Srinivasan, A.]]
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[[Category: Srinivasan A]]
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[[Category: Vikram, G.]]
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[[Category: Vikram G]]
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[[Category: Amyloid]]
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[[Category: Amyloid beta]]
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[[Category: Amyloidosis]]
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[[Category: Disulfide bond]]
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[[Category: Heptapeptide]]
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[[Category: Hydrolase]]
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[[Category: Lipid degradation]]
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[[Category: Metal-binding]]
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[[Category: Phospholipase a2]]
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[[Category: Protease inhibitor]]
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[[Category: Proteoglycan]]
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[[Category: Secreted]]
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[[Category: Serine protease inhibitor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 21 10:16:54 2010''
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Current revision

Crystal structure of the complex formed between Phospholipase A2 with beta-amyloid fragment, Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met at 1.8 A resolution

PDB ID 3jti

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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