3lg8

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[[Image:3lg8.png|left|200px]]
 
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==Crystal structure of the C-terminal part of subunit E (E101-206) from Methanocaldococcus jannaschii of A1AO ATP synthase==
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The line below this paragraph, containing "STRUCTURE_3lg8", creates the "Structure Box" on the page.
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<StructureSection load='3lg8' size='340' side='right'caption='[[3lg8]], [[Resolution|resolution]] 4.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3lg8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LG8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LG8 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lg8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lg8 OCA], [https://pdbe.org/3lg8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lg8 RCSB], [https://www.ebi.ac.uk/pdbsum/3lg8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lg8 ProSAT]</span></td></tr>
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{{STRUCTURE_3lg8| PDB=3lg8 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/VATE_METJA VATE_METJA] Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lg/3lg8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lg8 ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The structure of the C-terminus of subunit E (E(101-206)) of Methanocaldococcus jannaschii A-ATP synthase was determined at 4.1 A. E(101-206) consist of a N-terminal globular domain with three alpha-helices and four antiparallel beta-strands and an alpha-helix at the very C-terminus. Comparison of M. jannaschii E(101-206) with the C-terminus E(81-198) subunit E from Pyrococcus horikoshii OT3 revealed that the kink in the C-terminal alpha-helix of E(81-198), involved in dimer formation, is absent in M. jannaschii E(101-206). Whereas a major dimeric surface interface is present between the P. horikoshii E(81-198) molecules in the asymmetric unit, no such interaction could be found in the M. jannaschii E(101-206) molecules. To verify the oligomeric behaviour, the low resolution structure of the recombinant E(85-206) from M. jannaschii was determined using small angle X-ray scattering. Rigid body modeling of two copies of one of the monomer established a fit with a tail to tail arrangement.
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===Crystal structure of the C-terminal part of subunit E (E101-206) from Methanocaldococcus jannaschii of A1AO ATP synthase===
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Crystal and solution structure of the C-terminal part of the Methanocaldococcus jannaschii A(1)A (O) ATP synthase subunit E revealed by X-ray diffraction and small-angle X-ray scattering.,Balakrishna AM, Manimekalai MS, Hunke C, Gayen S, Rossle M, Jeyakanthan J, Gruber G J Bioenerg Biomembr. 2010 Jun 23. PMID:20571891<ref>PMID:20571891</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_20571891}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 3lg8" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 20571891 is the PubMed ID number.
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{{ABSTRACT_PUBMED_20571891}}
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==About this Structure==
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[[3lg8]] is a 2 chain structure of [[ATP synthase]] with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LG8 OCA].
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==See Also==
==See Also==
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*[[ATP synthase]]
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*[[ATPase 3D structures|ATPase 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:20571891</ref><ref group="xtra">PMID:17189637</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
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[[Category: Balakrishna, A M.]]
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[[Category: Balakrishna AM]]
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[[Category: Gayen, S.]]
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[[Category: Gayen S]]
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[[Category: Gruber, G.]]
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[[Category: Gruber G]]
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[[Category: Hunke, C.]]
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[[Category: Hunke C]]
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[[Category: Jeyakanthan, J.]]
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[[Category: Jeyakanthan J]]
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[[Category: Manimekalai, M S.S.]]
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[[Category: Manimekalai MSS]]
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[[Category: Archaea]]
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[[Category: Hydrolase]]
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[[Category: Peripheral stalk]]
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[[Category: Structural protein]]
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[[Category: Transport protein]]
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Current revision

Crystal structure of the C-terminal part of subunit E (E101-206) from Methanocaldococcus jannaschii of A1AO ATP synthase

PDB ID 3lg8

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