3m4z

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'''Unreleased structure'''
 
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The entry 3m4z is ON HOLD until Paper Publication
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==Crystal Structure of B. subtilis ferrochelatase with Cobalt bound at the active site==
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<StructureSection load='3m4z' size='340' side='right'caption='[[3m4z]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3m4z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M4Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3M4Z FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3m4z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m4z OCA], [https://pdbe.org/3m4z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3m4z RCSB], [https://www.ebi.ac.uk/pdbsum/3m4z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3m4z ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CPFC_BACSU CPFC_BACSU] Involved in coproporphyrin-dependent heme b biosynthesis (PubMed:25646457, PubMed:25908396). Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III (PubMed:25646457, PubMed:25908396). It can also insert iron into protoporphyrin IX (PubMed:1459957, PubMed:8119288, PubMed:21052751, PubMed:25646457). Has weaker activity with 2,4 disulfonate, deuteroporphyrin and 2,4 hydroxyethyl (PubMed:25646457, PubMed:12761666). In vitro, can also use Zn(2+) or Cu(2+) (PubMed:8119288, PubMed:16140324, PubMed:21052751, PubMed:12761666).<ref>PMID:12761666</ref> <ref>PMID:1459957</ref> <ref>PMID:16140324</ref> <ref>PMID:21052751</ref> <ref>PMID:25646457</ref> <ref>PMID:25826316</ref> <ref>PMID:25908396</ref> <ref>PMID:8119288</ref>
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Authors: Soderberg, C.A.G., Hansson, M.D., Sreekanth, R., Al-Karadaghi, S., Hansson, M.
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==See Also==
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*[[Ferrochelatase 3D structures|Ferrochelatase 3D structures]]
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Description: Crystal Structure of B. subtilis ferrochelatase with Cobalt bound at the active site
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== References ==
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<references/>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 10 10:57:09 2010''
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__TOC__
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</StructureSection>
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[[Category: Bacillus subtilis]]
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[[Category: Large Structures]]
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[[Category: Al-Karadaghi S]]
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[[Category: Hansson M]]
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[[Category: Hansson MD]]
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[[Category: Soderberg CAG]]
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[[Category: Sreekanth R]]

Current revision

Crystal Structure of B. subtilis ferrochelatase with Cobalt bound at the active site

PDB ID 3m4z

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