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3mgx

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==Crystal Structure of P450 OxyD that is involved in the Biosynthesis of Vancomycin-type Antibiotics==
==Crystal Structure of P450 OxyD that is involved in the Biosynthesis of Vancomycin-type Antibiotics==
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<StructureSection load='3mgx' size='340' side='right' caption='[[3mgx]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='3mgx' size='340' side='right'caption='[[3mgx]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3mgx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Amycolatopsis_balhimycetica Amycolatopsis balhimycetica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MGX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MGX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3mgx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Amycolatopsis_balhimycina Amycolatopsis balhimycina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MGX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MGX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">oxyD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208443 Amycolatopsis balhimycetica])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Unspecific_monooxygenase Unspecific monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.14.1 1.14.14.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mgx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mgx OCA], [https://pdbe.org/3mgx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mgx RCSB], [https://www.ebi.ac.uk/pdbsum/3mgx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mgx ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mgx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mgx OCA], [http://pdbe.org/3mgx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3mgx RCSB], [http://www.ebi.ac.uk/pdbsum/3mgx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3mgx ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q939Y1_AMYBA Q939Y1_AMYBA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mg/3mgx_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mg/3mgx_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Amycolatopsis balhimycetica]]
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[[Category: Amycolatopsis balhimycina]]
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[[Category: Unspecific monooxygenase]]
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[[Category: Large Structures]]
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[[Category: Cryle, M J]]
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[[Category: Cryle MJ]]
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[[Category: Schlichting, I]]
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[[Category: Schlichting I]]
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[[Category: Carrier protein]]
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[[Category: Cytochrome p450 oxidase]]
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[[Category: Haem protein]]
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[[Category: Oxidoreductase]]
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[[Category: Vancomycin biosynthesis]]
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Current revision

Crystal Structure of P450 OxyD that is involved in the Biosynthesis of Vancomycin-type Antibiotics

PDB ID 3mgx

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