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3nii

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==The structure of UBR box (KIAA)==
==The structure of UBR box (KIAA)==
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<StructureSection load='3nii' size='340' side='right' caption='[[3nii]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='3nii' size='340' side='right'caption='[[3nii]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3nii]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NII OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NII FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3nii]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NII OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NII FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3nih|3nih]], [[3nij|3nij]], [[3nik|3nik]], [[3nil|3nil]], [[3nim|3nim]], [[3nin|3nin]], [[3nis|3nis]], [[3nit|3nit]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nii OCA], [http://pdbe.org/3nii PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nii RCSB], [http://www.ebi.ac.uk/pdbsum/3nii PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nii ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nii OCA], [https://pdbe.org/3nii PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nii RCSB], [https://www.ebi.ac.uk/pdbsum/3nii PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nii ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/UBR1_YEAST UBR1_YEAST]] Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
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[https://www.uniprot.org/uniprot/UBR1_YEAST UBR1_YEAST] Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ni/3nii_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ni/3nii_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 3nii" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3nii" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Ubiquitin protein ligase 3D structures|Ubiquitin protein ligase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 18824]]
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[[Category: Large Structures]]
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[[Category: Choi, W S]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Jeong, B C]]
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[[Category: Choi WS]]
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[[Category: Lee, M R]]
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[[Category: Jeong B-C]]
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[[Category: Song, H K]]
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[[Category: Lee M-R]]
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[[Category: E3 ubiquitin ligase]]
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[[Category: Song HK]]
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[[Category: Ligase]]
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[[Category: Metal binding protein]]
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[[Category: N-end rule]]
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[[Category: Ubr box]]
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[[Category: Zinc-binding protein]]
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Current revision

The structure of UBR box (KIAA)

PDB ID 3nii

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