This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3od5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (16:54, 1 November 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Crystal structure of active caspase-6 bound with Ac-VEID-CHO==
==Crystal structure of active caspase-6 bound with Ac-VEID-CHO==
-
<StructureSection load='3od5' size='340' side='right' caption='[[3od5]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
+
<StructureSection load='3od5' size='340' side='right'caption='[[3od5]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3od5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OD5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OD5 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3od5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OD5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OD5 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=ASA:ASPARTIC+ALDEHYDE'>ASA</scene></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=ASA:ASPARTIC+ALDEHYDE'>ASA</scene>, <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3nr2|3nr2]]</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3od5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3od5 OCA], [https://pdbe.org/3od5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3od5 RCSB], [https://www.ebi.ac.uk/pdbsum/3od5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3od5 ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Caspase-6 Caspase-6], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.59 3.4.22.59] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3od5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3od5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3od5 RCSB], [http://www.ebi.ac.uk/pdbsum/3od5 PDBsum]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/CASP6_HUMAN CASP6_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
+
[https://www.uniprot.org/uniprot/CASP6_HUMAN CASP6_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 19: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 3od5" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
-
*[[Caspase|Caspase]]
+
*[[Caspase 3D structures|Caspase 3D structures]]
*[[Caspase-6 and neurodegeneration|Caspase-6 and neurodegeneration]]
*[[Caspase-6 and neurodegeneration|Caspase-6 and neurodegeneration]]
-
*[[Molecular Playground/Caspase-6 (new)|Molecular Playground/Caspase-6 (new)]]
 
*[[Molecular Playground/Caspase-6 and neurodegeneration|Molecular Playground/Caspase-6 and neurodegeneration]]
*[[Molecular Playground/Caspase-6 and neurodegeneration|Molecular Playground/Caspase-6 and neurodegeneration]]
*[[User:Kevin Buadlart Dagbay|User:Kevin Buadlart Dagbay]]
*[[User:Kevin Buadlart Dagbay|User:Kevin Buadlart Dagbay]]
Line 30: Line 29:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Caspase-6]]
 
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Cao, Q]]
+
[[Category: Large Structures]]
-
[[Category: Liu, X]]
+
[[Category: Cao Q]]
-
[[Category: Su, X D]]
+
[[Category: Liu X]]
-
[[Category: Wang, K T]]
+
[[Category: Su X-D]]
-
[[Category: Wang, X J]]
+
[[Category: Wang K-T]]
-
[[Category: Apoptotic protease]]
+
[[Category: Wang X-J]]
-
[[Category: Caspase domain]]
+
-
[[Category: Hydrolase-hydrolase inhibitor complex]]
+

Current revision

Crystal structure of active caspase-6 bound with Ac-VEID-CHO

PDB ID 3od5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3od5"
Personal tools