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3pir

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Current revision (17:06, 1 November 2023) (edit) (undo)
 
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<StructureSection load='3pir' size='340' side='right'caption='[[3pir]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
<StructureSection load='3pir' size='340' side='right'caption='[[3pir]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3pir]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PIR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PIR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3pir]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PIR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PIR FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1x1s|1x1s]], [[3kkp|3kkp]], [[3kko|3kko]], [[3kkm|3kkm]], [[3pit|3pit]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mras, Xras ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pir OCA], [https://pdbe.org/3pir PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pir RCSB], [https://www.ebi.ac.uk/pdbsum/3pir PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pir ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pir OCA], [https://pdbe.org/3pir PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pir RCSB], [https://www.ebi.ac.uk/pdbsum/3pir PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pir ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/RASM_MOUSE RASM_MOUSE]] May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway (By similarity).
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[https://www.uniprot.org/uniprot/RASM_MOUSE RASM_MOUSE] May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Hirai, R]]
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[[Category: Hirai R]]
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[[Category: Hu, L]]
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[[Category: Hu L]]
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[[Category: Ijiri, Y]]
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[[Category: Ijiri Y]]
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[[Category: Kataoka, T]]
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[[Category: Kataoka T]]
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[[Category: Liao, J]]
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[[Category: Liao J]]
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[[Category: Matsumoto, K]]
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[[Category: Matsumoto K]]
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[[Category: Muraoka, S]]
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[[Category: Muraoka S]]
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[[Category: Shima, F]]
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[[Category: Shima F]]
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[[Category: Gtp-binding]]
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[[Category: Gtpase]]
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[[Category: Signaling protein]]
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Current revision

Crystal structure of M-RasD41E in complex with GppNHp (type 1)

PDB ID 3pir

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