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3q2f

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==Crystal Structure of the bromodomain of human BAZ2B in complex with a triazolo ligand==
==Crystal Structure of the bromodomain of human BAZ2B in complex with a triazolo ligand==
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<StructureSection load='3q2f' size='340' side='right' caption='[[3q2f]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
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<StructureSection load='3q2f' size='340' side='right'caption='[[3q2f]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3q2f]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q2F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q2F FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3q2f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q2F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q2F FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OAM:4-{4-[3-(1H-IMIDAZOL-1-YL)PROPYL]-5-METHYL-4H-1,2,4-TRIAZOL-3-YL}-1-METHYL-1H-PYRAZOL-5-AMINE'>OAM</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.06&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3g0l|3g0l]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OAM:4-{4-[3-(1H-IMIDAZOL-1-YL)PROPYL]-5-METHYL-4H-1,2,4-TRIAZOL-3-YL}-1-METHYL-1H-PYRAZOL-5-AMINE'>OAM</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAZ2B, KIAA1476 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q2f OCA], [https://pdbe.org/3q2f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q2f RCSB], [https://www.ebi.ac.uk/pdbsum/3q2f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q2f ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q2f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q2f RCSB], [http://www.ebi.ac.uk/pdbsum/3q2f PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN]] May play a role in transcriptional regulation interacting with ISWI.
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[https://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN] May play a role in transcriptional regulation interacting with ISWI.
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==See Also==
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*[[Bromodomain adjacent to zinc finger 3D structures|Bromodomain adjacent to zinc finger 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H]]
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[[Category: Large Structures]]
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[[Category: Bountra, C]]
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[[Category: Arrowsmith CH]]
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[[Category: Delft, F von]]
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[[Category: Bountra C]]
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[[Category: Edwards, A M]]
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[[Category: Edwards AM]]
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[[Category: Felletar, I]]
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[[Category: Felletar I]]
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[[Category: Filippakopoulos, P]]
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[[Category: Filippakopoulos P]]
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[[Category: Keates, T]]
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[[Category: Keates T]]
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[[Category: Knapp, S]]
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[[Category: Knapp S]]
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[[Category: Muniz, J R.C]]
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[[Category: Muniz JRC]]
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[[Category: Picaud, S]]
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[[Category: Picaud S]]
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[[Category: Structural genomic]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J]]
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[[Category: Von Delft F]]
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[[Category: Bazb2]]
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[[Category: Bromodomain adjacent to zinc finger domain]]
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[[Category: Kiaa1476]]
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[[Category: Sgc]]
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[[Category: Transcription]]
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[[Category: Walp4]]
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Current revision

Crystal Structure of the bromodomain of human BAZ2B in complex with a triazolo ligand

PDB ID 3q2f

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