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3qbd

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==3-Dehydroquinate Synthase (aroB) from Mycobacterium tuberculosis in complex with NAD==
==3-Dehydroquinate Synthase (aroB) from Mycobacterium tuberculosis in complex with NAD==
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<StructureSection load='3qbd' size='340' side='right' caption='[[3qbd]], [[Resolution|resolution]] 2.47&Aring;' scene=''>
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<StructureSection load='3qbd' size='340' side='right'caption='[[3qbd]], [[Resolution|resolution]] 2.47&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3qbd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QBD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QBD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3qbd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QBD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QBD FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.47&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qbe|3qbe]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aroB, MRA_2566 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qbd OCA], [https://pdbe.org/3qbd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qbd RCSB], [https://www.ebi.ac.uk/pdbsum/3qbd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qbd ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_synthase 3-dehydroquinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.4 4.2.3.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qbd OCA], [http://pdbe.org/3qbd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3qbd RCSB], [http://www.ebi.ac.uk/pdbsum/3qbd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3qbd ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AROB_MYCTU AROB_MYCTU] Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).[HAMAP-Rule:MF_00110]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 3-dehydroquinate synthase]]
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[[Category: Large Structures]]
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[[Category: Myctu]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Chen, T J]]
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[[Category: Chen TJ]]
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[[Category: Cheng, W C]]
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[[Category: Cheng WC]]
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[[Category: Wang, W C]]
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[[Category: Wang WC]]
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[[Category: Lyase]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Rossmann-fold]]
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[[Category: Shikimate pathway]]
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Current revision

3-Dehydroquinate Synthase (aroB) from Mycobacterium tuberculosis in complex with NAD

PDB ID 3qbd

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