3qkz

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (17:13, 1 November 2023) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Crystal structure of mutant His269Arg AKR1B14==
==Crystal structure of mutant His269Arg AKR1B14==
-
<StructureSection load='3qkz' size='340' side='right' caption='[[3qkz]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
+
<StructureSection load='3qkz' size='340' side='right'caption='[[3qkz]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3qkz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QKZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QKZ FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3qkz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QKZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QKZ FirstGlance]. <br>
-
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene><br>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.87&#8491;</td></tr>
-
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3o3r|3o3r]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
-
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Akr1b7, rCG_28223 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qkz OCA], [https://pdbe.org/3qkz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qkz RCSB], [https://www.ebi.ac.uk/pdbsum/3qkz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qkz ProSAT]</span></td></tr>
-
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qkz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qkz RCSB], [http://www.ebi.ac.uk/pdbsum/3qkz PDBsum]</span></td></tr>
+
</table>
-
<table>
+
== Function ==
 +
[https://www.uniprot.org/uniprot/ALD1_RAT ALD1_RAT] Reduces a broad range of aliphatic and aromatic aldehydes to the corresponding alcohols. May play a role in the metabolism of xenobiotic aromatic aldehydes.<ref>PMID:21048316</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 14: Line 16:
Structure of the His269Arg mutant of the rat aldose reductase-like protein AKR1B14 complexed with NADPH.,Sundaram K, Endo S, Matsunaga T, Tanaka N, Hara A, El-Kabbani O Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Apr 1;68(Pt 4):400-3. Epub, 2012 Mar 27. PMID:22505406<ref>PMID:22505406</ref>
Structure of the His269Arg mutant of the rat aldose reductase-like protein AKR1B14 complexed with NADPH.,Sundaram K, Endo S, Matsunaga T, Tanaka N, Hara A, El-Kabbani O Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Apr 1;68(Pt 4):400-3. Epub, 2012 Mar 27. PMID:22505406<ref>PMID:22505406</ref>
-
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 3qkz" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Aldo-keto reductase 3D structures|Aldo-keto reductase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
-
[[Category: El-Kabbani, O.]]
+
[[Category: El-Kabbani O]]
-
[[Category: Sundaram, K.]]
+
[[Category: Sundaram K]]
-
[[Category: Akr1b14]]
+
-
[[Category: Aldose reductase-like protein]]
+
-
[[Category: Oxidoreductase]]
+

Current revision

Crystal structure of mutant His269Arg AKR1B14

PDB ID 3qkz

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3qkz"
Personal tools