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3rke
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3rke is ON HOLD Authors: Dube, D., Singh, R.P., Sinha, M., Singh, A.K., Kaur, P., Sharma, S., Singh, T.P. Description: Crystal Structure of goat La...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of goat Lactoperoxidase complexed with a tightly bound inhibitor, 4-aminophenyl-4H-imidazole-1-yl methanone at 2.3 A resolution== | |
| + | <StructureSection load='3rke' size='340' side='right'caption='[[3rke]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3rke]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RKE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RKE FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=MZZ:(4-AMINOPHENYL)-IMIDAZOL-1-YL-METHANONE'>MZZ</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rke FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rke OCA], [https://pdbe.org/3rke PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rke RCSB], [https://www.ebi.ac.uk/pdbsum/3rke PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rke ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PERL_CAPHI PERL_CAPHI] Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN) (PubMed:10894086). May protect the udder from infection and promote growth in newborns. Inhibits growth of several fungi including A.niger, Trichoderma species, C.cassicola, P.meadii and C.salmonicolor (PubMed:10894086). Does not have anti-fungal activity towards C.albicans and Pythium species (PubMed:10894086). Inhibits growth of several Gram-positive bacteria including some Staphylococcus species and Gram-negative bacteria including E.coli, P.aeruginosa and some Salmonella species (PubMed:10894086).<ref>PMID:10894086</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Lactoperoxidase|Lactoperoxidase]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Capra hircus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Dube D]] | ||
| + | [[Category: Kaur P]] | ||
| + | [[Category: Sharma S]] | ||
| + | [[Category: Singh AK]] | ||
| + | [[Category: Singh RP]] | ||
| + | [[Category: Singh TP]] | ||
| + | [[Category: Sinha M]] | ||
Current revision
Crystal Structure of goat Lactoperoxidase complexed with a tightly bound inhibitor, 4-aminophenyl-4H-imidazole-1-yl methanone at 2.3 A resolution
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Categories: Capra hircus | Large Structures | Dube D | Kaur P | Sharma S | Singh AK | Singh RP | Singh TP | Sinha M
