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3suw

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==Crystal structure of beta-hexosaminidase from Paenibacillus sp. TS12 in complex with NHAc-CAS==
==Crystal structure of beta-hexosaminidase from Paenibacillus sp. TS12 in complex with NHAc-CAS==
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<StructureSection load='3suw' size='340' side='right' caption='[[3suw]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='3suw' size='340' side='right'caption='[[3suw]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3suw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Paenibacillus Paenibacillus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SUW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SUW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3suw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Paenibacillus_sp._TS12 Paenibacillus sp. TS12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SUW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SUW FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GC2:6-ACETAMIDO-6-DEOXY-CASTANOSPERMINE'>GC2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3sur|3sur]], [[3sus|3sus]], [[3sut|3sut]], [[3suu|3suu]], [[3suv|3suv]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GC2:6-ACETAMIDO-6-DEOXY-CASTANOSPERMINE'>GC2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Hex1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=44249 Paenibacillus])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3suw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3suw OCA], [https://pdbe.org/3suw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3suw RCSB], [https://www.ebi.ac.uk/pdbsum/3suw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3suw ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>
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</table>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3suw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3suw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3suw RCSB], [http://www.ebi.ac.uk/pdbsum/3suw PDBsum]</span></td></tr>
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== Function ==
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<table>
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[https://www.uniprot.org/uniprot/D2KW09_9BACL D2KW09_9BACL]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Gaining insight into the inhibition of glycoside hydrolase family 20 exo-beta-N-acetylhexosaminidases using a structural approach.,Sumida T, Stubbs KA, Ito M, Yokoyama S Org Biomol Chem. 2012 Apr 7;10(13):2607-12. Epub 2012 Feb 27. PMID:22367352<ref>PMID:22367352</ref>
Gaining insight into the inhibition of glycoside hydrolase family 20 exo-beta-N-acetylhexosaminidases using a structural approach.,Sumida T, Stubbs KA, Ito M, Yokoyama S Org Biomol Chem. 2012 Apr 7;10(13):2607-12. Epub 2012 Feb 27. PMID:22367352<ref>PMID:22367352</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3suw" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
*[[Beta-Hexosaminidase|Beta-Hexosaminidase]]
*[[Beta-Hexosaminidase|Beta-Hexosaminidase]]
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*[[Beta-Hexosaminidase 3D structures|Beta-Hexosaminidase 3D structures]]
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*[[Beta-N-acetylhexosaminidase 3D structures|Beta-N-acetylhexosaminidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Beta-N-acetylhexosaminidase]]
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[[Category: Large Structures]]
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[[Category: Paenibacillus]]
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[[Category: Paenibacillus sp. TS12]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Sumida T]]
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[[Category: Sumida, T.]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S.]]
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[[Category: Carbohydrate/sugar binding]]
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[[Category: Hydrolase]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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[[Category: Tim barrel]]
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Current revision

Crystal structure of beta-hexosaminidase from Paenibacillus sp. TS12 in complex with NHAc-CAS

PDB ID 3suw

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