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3ti6

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==Crystal structure of 2009 pandemic H1N1 neuraminidase complexed with oseltamivir==
==Crystal structure of 2009 pandemic H1N1 neuraminidase complexed with oseltamivir==
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<StructureSection load='3ti6' size='340' side='right' caption='[[3ti6]], [[Resolution|resolution]] 1.69&Aring;' scene=''>
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<StructureSection load='3ti6' size='340' side='right'caption='[[3ti6]], [[Resolution|resolution]] 1.69&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ti6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/I09a0 I09a0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TI6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TI6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ti6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/California/04/2009(H1N1)) Influenza A virus (A/California/04/2009(H1N1))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TI6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TI6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=G39:(3R,4R,5S)-4-(ACETYLAMINO)-5-AMINO-3-(PENTAN-3-YLOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC+ACID'>G39</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.69&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3nss|3nss]], [[3ti3|3ti3]], [[3ti4|3ti4]], [[3ti5|3ti5]], [[3ti8|3ti8]], [[3tia|3tia]], [[3tib|3tib]], [[3tic|3tic]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=G39:(3R,4R,5S)-4-(ACETYLAMINO)-5-AMINO-3-(PENTAN-3-YLOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC+ACID'>G39</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=641501 I09A0])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ti6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ti6 OCA], [https://pdbe.org/3ti6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ti6 RCSB], [https://www.ebi.ac.uk/pdbsum/3ti6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ti6 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ti6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ti6 OCA], [http://pdbe.org/3ti6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ti6 RCSB], [http://www.ebi.ac.uk/pdbsum/3ti6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ti6 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/C3W5S3_I09A0 C3W5S3_I09A0]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Neuraminidase|Neuraminidase]]
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*[[Neuraminidase 3D structures|Neuraminidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: I09a0]]
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[[Category: Large Structures]]
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[[Category: Feng, E]]
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[[Category: Feng E]]
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[[Category: Gao, F]]
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[[Category: Gao F]]
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[[Category: Gao, G F]]
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[[Category: Gao GF]]
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[[Category: He, J]]
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[[Category: He J]]
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[[Category: Jiang, H]]
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[[Category: Jiang H]]
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[[Category: Li, Q]]
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[[Category: Li Q]]
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[[Category: Liu, H]]
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[[Category: Liu H]]
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[[Category: Liu, J]]
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[[Category: Liu J]]
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[[Category: Liu, Y]]
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[[Category: Liu Y]]
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[[Category: Qi, J]]
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[[Category: Qi J]]
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[[Category: Vavricka, C J]]
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[[Category: Vavricka CJ]]
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[[Category: Wang, J]]
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[[Category: Wang J]]
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[[Category: Wang, M]]
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[[Category: Wang M]]
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[[Category: Wu, Y]]
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[[Category: Wu Y]]
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[[Category: 6-bladed beta-propeller]]
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[[Category: Antiviral]]
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[[Category: Calcium binding]]
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[[Category: Glycosylation]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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Current revision

Crystal structure of 2009 pandemic H1N1 neuraminidase complexed with oseltamivir

PDB ID 3ti6

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