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3tib

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==Crystal structure of 1957 pandemic H2N2 neuraminidase complexed with laninamivir octanoate==
==Crystal structure of 1957 pandemic H2N2 neuraminidase complexed with laninamivir octanoate==
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<StructureSection load='3tib' size='340' side='right' caption='[[3tib]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='3tib' size='340' side='right'caption='[[3tib]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3tib]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus Influenza a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TIB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TIB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3tib]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/RI/5+/1957(H2N2)) Influenza A virus (A/RI/5+/1957(H2N2))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TIB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TIB FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=LVO:5-(ACETYLAMINO)-2,6-ANHYDRO-4-CARBAMIMIDAMIDO-3,4,5-TRIDEOXY-7-O-METHYL-9-O-OCTANOYL-D-GLYCERO-D-GALACTO-NON-2-ENONIC+ACID'>LVO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.201&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ti3|3ti3]], [[3ti4|3ti4]], [[3ti5|3ti5]], [[3ti6|3ti6]], [[3ti8|3ti8]], [[3tia|3tia]], [[3tic|3tic]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=LVO:5-(ACETYLAMINO)-2,6-ANHYDRO-4-CARBAMIMIDAMIDO-3,4,5-TRIDEOXY-7-O-METHYL-9-O-OCTANOYL-D-GLYCERO-D-GALACTO-NON-2-ENONIC+ACID'>LVO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tib OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tib RCSB], [http://www.ebi.ac.uk/pdbsum/3tib PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tib OCA], [https://pdbe.org/3tib PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tib RCSB], [https://www.ebi.ac.uk/pdbsum/3tib PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tib ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q194T1_9INFA Q194T1_9INFA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3tib" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Neuraminidase|Neuraminidase]]
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*[[Neuraminidase 3D structures|Neuraminidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Influenza a virus]]
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[[Category: Large Structures]]
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[[Category: Feng, E]]
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[[Category: Feng E]]
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[[Category: Gao, F]]
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[[Category: Gao F]]
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[[Category: Gao, G F]]
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[[Category: Gao GF]]
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[[Category: He, J]]
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[[Category: He J]]
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[[Category: Jiang, H]]
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[[Category: Jiang H]]
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[[Category: Li, Q]]
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[[Category: Li Q]]
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[[Category: Liu, H]]
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[[Category: Liu H]]
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[[Category: Liu, J]]
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[[Category: Liu J]]
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[[Category: Liu, Y]]
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[[Category: Liu Y]]
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[[Category: Qi, J]]
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[[Category: Qi J]]
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[[Category: Vavricka, C J]]
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[[Category: Vavricka CJ]]
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[[Category: Wang, J]]
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[[Category: Wang J]]
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[[Category: Wang, M]]
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[[Category: Wang M]]
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[[Category: Wu, Y]]
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[[Category: Wu Y]]
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[[Category: 6-bladed beta-propeller]]
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[[Category: Antiviral]]
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[[Category: Calcium binding]]
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[[Category: Glycosylation]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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Current revision

Crystal structure of 1957 pandemic H2N2 neuraminidase complexed with laninamivir octanoate

PDB ID 3tib

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