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3u8q
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3u8q is ON HOLD Authors: Shukla, P.K. , Gautam, L., Sinha, M. , Kaur, P. , Sharma, S. , Singh, T.P. Description: Crystal Structure of C-lobe of Bov...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Phenyl-Propanolamine at 1.97 A Resolution== | |
| + | <StructureSection load='3u8q' size='340' side='right'caption='[[3u8q]], [[Resolution|resolution]] 1.97Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3u8q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U8Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U8Q FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.97Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NPU:(1R,2R)-2-AMINO-1-PHENYLPROPAN-1-OL'>NPU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u8q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u8q OCA], [https://pdbe.org/3u8q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u8q RCSB], [https://www.ebi.ac.uk/pdbsum/3u8q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u8q ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TRFL_BOVIN TRFL_BOVIN] Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> Lactotransferrin has antimicrobial activity. The most effective inhibitory activity was seen against E.coli and P.aeruginosa.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> Lactoferricin B is an antimicrobial peptide. Inhibits the growth of Gram-negative and Gram-positive bacteria.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Lactoferrin|Lactoferrin]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bos taurus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Gautam L]] | ||
| + | [[Category: Kaur P]] | ||
| + | [[Category: Sharma S]] | ||
| + | [[Category: Shukla PK]] | ||
| + | [[Category: Singh TP]] | ||
| + | [[Category: Sinha M]] | ||
Current revision
Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Phenyl-Propanolamine at 1.97 A Resolution
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Categories: Bos taurus | Large Structures | Gautam L | Kaur P | Sharma S | Shukla PK | Singh TP | Sinha M
