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3uci

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==Crystal structure of Rhodostomin ARLDDL mutant==
==Crystal structure of Rhodostomin ARLDDL mutant==
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<StructureSection load='3uci' size='340' side='right' caption='[[3uci]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
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<StructureSection load='3uci' size='340' side='right'caption='[[3uci]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3uci]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Agkistrodon_rhodostoma Agkistrodon rhodostoma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UCI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UCI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3uci]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UCI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UCI FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RHOD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=8717 Agkistrodon rhodostoma])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3uci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uci OCA], [http://pdbe.org/3uci PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3uci RCSB], [http://www.ebi.ac.uk/pdbsum/3uci PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3uci ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uci OCA], [https://pdbe.org/3uci PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uci RCSB], [https://www.ebi.ac.uk/pdbsum/3uci PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uci ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH]] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity). Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).
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[https://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity). Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Agkistrodon rhodostoma]]
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[[Category: Calloselasma rhodostoma]]
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[[Category: Chang, Y S]]
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[[Category: Large Structures]]
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[[Category: Chang, Y T]]
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[[Category: Chang YS]]
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[[Category: Chen, C Y]]
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[[Category: Chang YT]]
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[[Category: Chen, Y C]]
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[[Category: Chen CY]]
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[[Category: Chuang, W J]]
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[[Category: Chen YC]]
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[[Category: Huang, C H]]
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[[Category: Chuang WJ]]
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[[Category: Shiu, J H]]
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[[Category: Huang CH]]
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[[Category: Disintegrin]]
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[[Category: Shiu JH]]
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[[Category: Integrin alphavbeta3]]
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[[Category: Toxin]]
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Current revision

Crystal structure of Rhodostomin ARLDDL mutant

PDB ID 3uci

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