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5m1x

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Current revision (18:20, 1 November 2023) (edit) (undo)
 
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<StructureSection load='5m1x' size='340' side='right'caption='[[5m1x]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='5m1x' size='340' side='right'caption='[[5m1x]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5m1x]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M1X OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5M1X FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5m1x]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M1X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5M1X FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RFA1, BUF2, RPA1, YAR007C, FUN3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5m1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m1x OCA], [http://pdbe.org/5m1x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m1x RCSB], [http://www.ebi.ac.uk/pdbsum/5m1x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m1x ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5m1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m1x OCA], [https://pdbe.org/5m1x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5m1x RCSB], [https://www.ebi.ac.uk/pdbsum/5m1x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5m1x ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RFA1_YEAST RFA1_YEAST]] Binds to single-stranded sequences participating in DNA replication in addition to those mediating transcriptional repression (URS1) and activation (CAR1). Stimulates the activity of a cognate strand exchange protein (SEP1). It cooperates with T-AG and DNA topoisomerase I to unwind template DNA containing the simian virus 40 origin of DNA replication.
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[https://www.uniprot.org/uniprot/RFA1_YEAST RFA1_YEAST] Binds to single-stranded sequences participating in DNA replication in addition to those mediating transcriptional repression (URS1) and activation (CAR1). Stimulates the activity of a cognate strand exchange protein (SEP1). It cooperates with T-AG and DNA topoisomerase I to unwind template DNA containing the simian virus 40 origin of DNA replication.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Baker's yeast]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Deshpande, I]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Eglinger, J]]
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[[Category: Deshpande I]]
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[[Category: Gasser, S M]]
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[[Category: Eglinger J]]
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[[Category: Gut, H]]
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[[Category: Gasser SM]]
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[[Category: Hegnauer, A M]]
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[[Category: Gut H]]
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[[Category: Hopfner, K P]]
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[[Category: Hegnauer AM]]
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[[Category: Hustedt, N]]
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[[Category: Hopfner KP]]
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[[Category: Pasero, P]]
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[[Category: Hustedt N]]
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[[Category: Poli, J]]
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[[Category: Pasero P]]
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[[Category: Seeber, A]]
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[[Category: Poli J]]
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[[Category: Shimada, K]]
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[[Category: Seeber A]]
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[[Category: Shinohara, M]]
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[[Category: Shimada K]]
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[[Category: Ob fold]]
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[[Category: Shinohara M]]
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[[Category: Replication]]
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Current revision

Crystal structure of S. cerevisiae Rfa1 N-OB domain mutant (K45E)

PDB ID 5m1x

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