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5mfx
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5mfx is ON HOLD until Paper Publication Authors: Jenkins, H.T., Ge, M., Chechik, M., Greive, S.J., Antson, A.A. Description: Zika NS3 helicase:RNA ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Zika NS3 helicase:RNA complex== | |
| + | <StructureSection load='5mfx' size='340' side='right'caption='[[5mfx]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5mfx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Zika_virus Zika virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MFX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MFX FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.598Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mfx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mfx OCA], [https://pdbe.org/5mfx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mfx RCSB], [https://www.ebi.ac.uk/pdbsum/5mfx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mfx ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A146CJH9_ZIKV A0A146CJH9_ZIKV] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859] | ||
| - | + | ==See Also== | |
| - | + | *[[Virus protease 3D structures|Virus protease 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Antson | + | [[Category: Zika virus]] |
| - | [[Category: Chechik | + | [[Category: Antson AA]] |
| - | [[Category: Ge | + | [[Category: Chechik M]] |
| - | [[Category: Jenkins | + | [[Category: Ge M]] |
| + | [[Category: Greive SJ]] | ||
| + | [[Category: Jenkins HT]] | ||
Current revision
Zika NS3 helicase:RNA complex
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Categories: Large Structures | Zika virus | Antson AA | Chechik M | Ge M | Greive SJ | Jenkins HT
