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3vkm

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==Protease-resistant mutant form of Human Galectin-8 in complex with sialyllactose and lactose==
==Protease-resistant mutant form of Human Galectin-8 in complex with sialyllactose and lactose==
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<StructureSection load='3vkm' size='340' side='right' caption='[[3vkm]], [[Resolution|resolution]] 2.98&Aring;' scene=''>
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<StructureSection load='3vkm' size='340' side='right'caption='[[3vkm]], [[Resolution|resolution]] 2.98&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3vkm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VKM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VKM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3vkm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VKM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VKM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.98&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4fqz|4fqz]], [[3vkl|3vkl]], [[3vkn|3vkn]], [[3vko|3vko]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=PRD_900004:beta-lactose'>PRD_900004</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LGALS8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vkm OCA], [https://pdbe.org/3vkm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vkm RCSB], [https://www.ebi.ac.uk/pdbsum/3vkm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vkm ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vkm OCA], [http://pdbe.org/3vkm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3vkm RCSB], [http://www.ebi.ac.uk/pdbsum/3vkm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3vkm ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LEG8_HUMAN LEG8_HUMAN]] Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.<ref>PMID:21288902</ref>
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[https://www.uniprot.org/uniprot/LEG8_HUMAN LEG8_HUMAN] Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.<ref>PMID:21288902</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 3vkm" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3vkm" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Galectin 3D structures|Galectin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Kamitori, S]]
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[[Category: Large Structures]]
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[[Category: Nakakita, S]]
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[[Category: Kamitori S]]
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[[Category: Nishi, N]]
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[[Category: Nakakita S]]
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[[Category: Teraoka, M]]
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[[Category: Nishi N]]
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[[Category: Yamashita, S]]
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[[Category: Teraoka M]]
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[[Category: Yoshida, H]]
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[[Category: Yamashita S]]
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[[Category: Beta-sandwich]]
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[[Category: Yoshida H]]
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[[Category: Carbohydrate binding]]
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[[Category: Oligosaccharide]]
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[[Category: Sugar binding protein]]
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Current revision

Protease-resistant mutant form of Human Galectin-8 in complex with sialyllactose and lactose

PDB ID 3vkm

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