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3vpn
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==Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant== | ==Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant== | ||
| - | <StructureSection load='3vpn' size='340' side='right' caption='[[3vpn]], [[Resolution|resolution]] 2.25Å' scene=''> | + | <StructureSection load='3vpn' size='340' side='right'caption='[[3vpn]], [[Resolution|resolution]] 2.25Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3vpn]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3vpn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VPN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VPN FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | <tr id=' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vpn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vpn OCA], [https://pdbe.org/3vpn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vpn RCSB], [https://www.ebi.ac.uk/pdbsum/3vpn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vpn ProSAT]</span></td></tr> |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/RIR2_HUMAN RIR2_HUMAN] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling. |
==See Also== | ==See Also== | ||
| - | *[[Ribonucleotide reductase|Ribonucleotide reductase]] | + | *[[Ribonucleotide reductase 3D structures|Ribonucleotide reductase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Chen | + | [[Category: Chen B]] |
| - | [[Category: Chen | + | [[Category: Chen X]] |
| - | [[Category: Liu | + | [[Category: Liu H]] |
| - | [[Category: Shao | + | [[Category: Shao J]] |
| - | [[Category: Xu | + | [[Category: Xu Z]] |
| - | [[Category: Yang | + | [[Category: Yang C]] |
| - | [[Category: Zhang | + | [[Category: Zhang L]] |
| - | [[Category: Zhu | + | [[Category: Zhu L]] |
| - | [[Category: Zhu | + | [[Category: Zhu W]] |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant
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Categories: Homo sapiens | Large Structures | Chen B | Chen X | Liu H | Shao J | Xu Z | Yang C | Zhang L | Zhu L | Zhu W
