3vqf
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3vqf is ON HOLD Authors: Akiyoshi, Y., Hamada, D., Goda, N., Tenno, T., Narita, H., Nakagawa, A., Furuse, M., Suzuki, M., Hiroaki, H. Description: ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure Analysis of the PDZ Domain Derived from the Tight Junction Regulating Protein== | |
| + | <StructureSection load='3vqf' size='340' side='right'caption='[[3vqf]], [[Resolution|resolution]] 1.20Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3vqf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VQF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VQF FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.199Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vqf OCA], [https://pdbe.org/3vqf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vqf RCSB], [https://www.ebi.ac.uk/pdbsum/3vqf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vqf ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LNX1_MOUSE LNX1_MOUSE] E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65. Isoform 2 provides an endocytic scaffold for IGSF5/JAM4. | ||
| - | + | ==See Also== | |
| - | + | *[[Ubiquitin protein ligase 3D structures|Ubiquitin protein ligase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Akiyoshi Y]] | ||
| + | [[Category: Furuse M]] | ||
| + | [[Category: Goda N]] | ||
| + | [[Category: Hamada D]] | ||
| + | [[Category: Hiroaki H]] | ||
| + | [[Category: Nakagawa A]] | ||
| + | [[Category: Narita H]] | ||
| + | [[Category: Suzuki M]] | ||
| + | [[Category: Tenno T]] | ||
Current revision
Crystal Structure Analysis of the PDZ Domain Derived from the Tight Junction Regulating Protein
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Categories: Large Structures | Mus musculus | Akiyoshi Y | Furuse M | Goda N | Hamada D | Hiroaki H | Nakagawa A | Narita H | Suzuki M | Tenno T
