This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3w76
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='3w76' size='340' side='right'caption='[[3w76]], [[Resolution|resolution]] 1.58Å' scene=''> | <StructureSection load='3w76' size='340' side='right'caption='[[3w76]], [[Resolution|resolution]] 1.58Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3w76]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3w76]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi_strain_CL_Brener Trypanosoma cruzi strain CL Brener]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W76 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W76 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene>, <scene name='pdbligand=W76:5-[2-(3-METHOXYPHENYL)ETHYL]-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC+ACID'>W76</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.58Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene>, <scene name='pdbligand=W76:5-[2-(3-METHOXYPHENYL)ETHYL]-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC+ACID'>W76</scene></td></tr> | |
| - | + | ||
| - | + | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w76 OCA], [https://pdbe.org/3w76 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w76 RCSB], [https://www.ebi.ac.uk/pdbsum/3w76 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w76 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w76 OCA], [https://pdbe.org/3w76 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w76 RCSB], [https://www.ebi.ac.uk/pdbsum/3w76 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w76 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/PYRD_TRYCC PYRD_TRYCC] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro. | |
==See Also== | ==See Also== | ||
| Line 18: | Line 16: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Trypanosoma cruzi strain CL Brener]] |
| - | [[Category: Aoki | + | [[Category: Aoki T]] |
| - | [[Category: Balogun | + | [[Category: Balogun EO]] |
| - | [[Category: Harada | + | [[Category: Harada S]] |
| - | [[Category: Hashimoto | + | [[Category: Hashimoto S]] |
| - | [[Category: Honma | + | [[Category: Honma T]] |
| - | [[Category: Iida | + | [[Category: Iida M]] |
| - | [[Category: Inaoka | + | [[Category: Inaoka DK]] |
| - | [[Category: Inoue | + | [[Category: Inoue M]] |
| - | [[Category: Kita | + | [[Category: Kita K]] |
| - | [[Category: Kuranaga | + | [[Category: Kuranaga T]] |
| - | [[Category: Lee | + | [[Category: Lee N]] |
| - | [[Category: Matsuoka | + | [[Category: Matsuoka S]] |
| - | [[Category: Nara | + | [[Category: Nara T]] |
| - | [[Category: Sakamoto | + | [[Category: Sakamoto K]] |
| - | [[Category: Shiba | + | [[Category: Shiba T]] |
| - | [[Category: Suzuki | + | [[Category: Suzuki S]] |
| - | [[Category: Tabuchi | + | [[Category: Tabuchi T]] |
| - | [[Category: Tanaka | + | [[Category: Tanaka A]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-4-189
| |||||||||||
Categories: Large Structures | Trypanosoma cruzi strain CL Brener | Aoki T | Balogun EO | Harada S | Hashimoto S | Honma T | Iida M | Inaoka DK | Inoue M | Kita K | Kuranaga T | Lee N | Matsuoka S | Nara T | Sakamoto K | Shiba T | Suzuki S | Tabuchi T | Tanaka A
