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3w86
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==Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with SH-1-96== | ==Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with SH-1-96== | ||
| - | <StructureSection load='3w86' size='340' side='right' caption='[[3w86]], [[Resolution|resolution]] 1.50Å' scene=''> | + | <StructureSection load='3w86' size='340' side='right'caption='[[3w86]], [[Resolution|resolution]] 1.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3w86]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3w86]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi_strain_CL_Brener Trypanosoma cruzi strain CL Brener]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W86 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W86 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene>, <scene name='pdbligand=W86:5-{4-[4-(METHOXYCARBONYL)PHENYL]BUTYL}-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC+ACID'>W86</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene>, <scene name='pdbligand=W86:5-{4-[4-(METHOXYCARBONYL)PHENYL]BUTYL}-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC+ACID'>W86</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w86 OCA], [https://pdbe.org/3w86 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w86 RCSB], [https://www.ebi.ac.uk/pdbsum/3w86 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w86 ProSAT]</span></td></tr> | |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PYRD_TRYCC PYRD_TRYCC] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro. |
==See Also== | ==See Also== | ||
| - | *[[Dihydroorotate dehydrogenase|Dihydroorotate dehydrogenase]] | + | *[[Dihydroorotate dehydrogenase 3D structures|Dihydroorotate dehydrogenase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Aoki | + | [[Category: Trypanosoma cruzi strain CL Brener]] |
| - | [[Category: Balogun | + | [[Category: Aoki T]] |
| - | [[Category: Harada | + | [[Category: Balogun EO]] |
| - | [[Category: Hashimoto | + | [[Category: Harada S]] |
| - | [[Category: Honma | + | [[Category: Hashimoto S]] |
| - | [[Category: Iida | + | [[Category: Honma T]] |
| - | [[Category: Inaoka | + | [[Category: Iida M]] |
| - | [[Category: Inoue | + | [[Category: Inaoka DK]] |
| - | [[Category: Kita | + | [[Category: Inoue M]] |
| - | [[Category: Kuranaga | + | [[Category: Kita K]] |
| - | [[Category: Lee | + | [[Category: Kuranaga T]] |
| - | [[Category: Matsuoka | + | [[Category: Lee N]] |
| - | [[Category: Montanari | + | [[Category: Matsuoka S]] |
| - | [[Category: Nara | + | [[Category: Montanari CA]] |
| - | [[Category: Rocha | + | [[Category: Nara T]] |
| - | [[Category: Sakamoto | + | [[Category: Rocha JR]] |
| - | [[Category: Shiba | + | [[Category: Sakamoto K]] |
| - | [[Category: Suzuki | + | [[Category: Shiba T]] |
| - | [[Category: Tabuchi | + | [[Category: Suzuki S]] |
| - | [[Category: Tanaka | + | [[Category: Tabuchi T]] |
| - | + | [[Category: Tanaka A]] | |
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Current revision
Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with SH-1-96
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Categories: Large Structures | Trypanosoma cruzi strain CL Brener | Aoki T | Balogun EO | Harada S | Hashimoto S | Honma T | Iida M | Inaoka DK | Inoue M | Kita K | Kuranaga T | Lee N | Matsuoka S | Montanari CA | Nara T | Rocha JR | Sakamoto K | Shiba T | Suzuki S | Tabuchi T | Tanaka A
