This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3wg3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:08, 8 November 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 3: Line 3:
<StructureSection load='3wg3' size='340' side='right'caption='[[3wg3]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
<StructureSection load='3wg3' size='340' side='right'caption='[[3wg3]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3wg3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Agrcy Agrcy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WG3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WG3 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3wg3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrocybe_cylindracea Agrocybe cylindracea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WG3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WG3 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3wg1|3wg1]], [[3wg2|3wg2]], [[3wg4|3wg4]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PRD_900132:Blood+group+A+H+type+2+antigen,+beta+anomer'>PRD_900132</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wg3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wg3 OCA], [http://pdbe.org/3wg3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wg3 RCSB], [http://www.ebi.ac.uk/pdbsum/3wg3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wg3 ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wg3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wg3 OCA], [https://pdbe.org/3wg3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wg3 RCSB], [https://www.ebi.ac.uk/pdbsum/3wg3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wg3 ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/ATLE_CYCAE ATLE_CYCAE] Anti-tumor lectin with DNase activity. Inhibits the growth of several tumor cell lines in vitro. Induces lymphocyte infiltration and necrosis of tumor cells in a mouse tumor model. Induces apoptosis in HeLa cells. Binds N-acetylneuraminyl lactose (N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucose) (PubMed:16051274).<ref>PMID:12757412</ref> <ref>PMID:16051274</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 17: Line 19:
</div>
</div>
<div class="pdbe-citations 3wg3" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3wg3" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Galectin 3D structures|Galectin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Agrcy]]
+
[[Category: Agrocybe cylindracea]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Hirabayashi, J]]
+
[[Category: Hirabayashi J]]
-
[[Category: Hu, D]]
+
[[Category: Hu D]]
-
[[Category: Kato, R]]
+
[[Category: Kato R]]
-
[[Category: Kuwabara, N]]
+
[[Category: Kuwabara N]]
-
[[Category: Makio, H]]
+
[[Category: Makio H]]
-
[[Category: Tateno, H]]
+
[[Category: Tateno H]]
-
[[Category: Galactose binding]]
+
-
[[Category: Galectin]]
+
-
[[Category: Sugar binding protein]]
+

Current revision

Crystal structure of Agrocybe cylindracea galectin with blood type A antigen tetraose

PDB ID 3wg3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3wg3"
Personal tools