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3wg2
From Proteopedia
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<StructureSection load='3wg2' size='340' side='right'caption='[[3wg2]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='3wg2' size='340' side='right'caption='[[3wg2]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3wg2]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3wg2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cyclocybe_aegerita Cyclocybe aegerita]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WG2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WG2 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wg2 OCA], [https://pdbe.org/3wg2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wg2 RCSB], [https://www.ebi.ac.uk/pdbsum/3wg2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wg2 ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ATLE_CYCAE ATLE_CYCAE] Anti-tumor lectin with DNase activity. Inhibits the growth of several tumor cell lines in vitro. Induces lymphocyte infiltration and necrosis of tumor cells in a mouse tumor model. Induces apoptosis in HeLa cells. Binds N-acetylneuraminyl lactose (N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucose) (PubMed:16051274).<ref>PMID:12757412</ref> <ref>PMID:16051274</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 3wg2" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 3wg2" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Galectin 3D structures|Galectin 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Cyclocybe aegerita]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Hirabayashi | + | [[Category: Hirabayashi J]] |
| - | [[Category: Hu | + | [[Category: Hu D]] |
| - | [[Category: Kato | + | [[Category: Kato R]] |
| - | [[Category: Kuwabara | + | [[Category: Kuwabara N]] |
| - | [[Category: Makio | + | [[Category: Makio H]] |
| - | [[Category: Tateno | + | [[Category: Tateno H]] |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal structure of Agrocybe cylindracea galectin mutant (N46A)
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Categories: Cyclocybe aegerita | Large Structures | Hirabayashi J | Hu D | Kato R | Kuwabara N | Makio H | Tateno H
