This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3wor

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:19, 8 November 2023) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Crystal structure of the DAP BII octapeptide complex==
==Crystal structure of the DAP BII octapeptide complex==
-
<StructureSection load='3wor' size='340' side='right' caption='[[3wor]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
+
<StructureSection load='3wor' size='340' side='right'caption='[[3wor]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3wor]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WOR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WOR FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3wor]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Pseudoxanthomonas_mexicana Pseudoxanthomonas mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WOR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WOR FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3woi|3woi]], [[3woj|3woj]], [[3wok|3wok]], [[3wol|3wol]], [[3wom|3wom]], [[3won|3won]], [[3woo|3woo]], [[3wop|3wop]], [[3woq|3woq]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wor OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wor RCSB], [http://www.ebi.ac.uk/pdbsum/3wor PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wor OCA], [https://pdbe.org/3wor PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wor RCSB], [https://www.ebi.ac.uk/pdbsum/3wor PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wor ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/DAPB2_PSEMX DAPB2_PSEMX] Exopeptidase that catalyzes the removal of dipeptide units (NH2-P2-P1-) from the free amino termini of oligopeptides and small proteins (PubMed:24598890, PubMed:8892831, PubMed:24827749). Peptide digestion is sequential and substrate recognition is non-specific, with the exception that Pro is not suitable as a P1 residue (PubMed:24827749). Removes many residues of bioactive oligopeptides such as angiotensin I and neuromedin N and cleaves also oxidized insulin B chain. Able to hydrolyze an X-Pro bond, an imido bond. No endopeptidase activity (PubMed:8892831). May play a physiological role in feeding (PubMed:24598890).<ref>PMID:24598890</ref> <ref>PMID:24827749</ref> <ref>PMID:8892831</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 15: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 3wor" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Fujimoto, M]]
+
[[Category: Homo sapiens]]
-
[[Category: Iizuka, I]]
+
[[Category: Large Structures]]
-
[[Category: Nonaka, T]]
+
[[Category: Pseudoxanthomonas mexicana]]
-
[[Category: Ogasawara, W]]
+
[[Category: Fujimoto M]]
-
[[Category: Roppongi, S]]
+
[[Category: Iizuka I]]
-
[[Category: Sakamoto, Y]]
+
[[Category: Nonaka T]]
-
[[Category: Suzuki, Y]]
+
[[Category: Ogasawara W]]
-
[[Category: Tanaka, N]]
+
[[Category: Roppongi S]]
-
[[Category: Tateoka, C]]
+
[[Category: Sakamoto Y]]
-
[[Category: Chymotrypsin fold]]
+
[[Category: Suzuki Y]]
-
[[Category: Hydrolase-hormone complex]]
+
[[Category: Tanaka N]]
-
[[Category: S46 peptidase]]
+
[[Category: Tateoka C]]

Current revision

Crystal structure of the DAP BII octapeptide complex

PDB ID 3wor

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3wor"
Personal tools