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4i3b

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==Crystal structure of fluorescent protein UnaG wild type==
==Crystal structure of fluorescent protein UnaG wild type==
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<StructureSection load='4i3b' size='340' side='right' caption='[[4i3b]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
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<StructureSection load='4i3b' size='340' side='right'caption='[[4i3b]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4i3b]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Angja Angja]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I3B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4I3B FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4i3b]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Anguilla_japonica Anguilla japonica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I3B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I3B FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BLR:3-[5-[(Z)-(4-ETHENYL-3-METHYL-5-OXIDANYLIDENE-PYRROL-2-YLIDENE)METHYL]-2-[[5-[(Z)-(3-ETHENYL-4-METHYL-5-OXIDANYLIDENE-PYRROL-2-YLIDENE)METHYL]-3-(3-HYDROXY-3-OXOPROPYL)-4-METHYL-1H-PYRROL-2-YL]METHYL]-4-METHYL-1H-PYRROL-3-YL]PROPANOIC+ACID'>BLR</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.199&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4i3c|4i3c]], [[4i3d|4i3d]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BLR:3-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(Z)-(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic+acid'>BLR</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i3b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i3b OCA], [http://pdbe.org/4i3b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4i3b RCSB], [http://www.ebi.ac.uk/pdbsum/4i3b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4i3b ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i3b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i3b OCA], [https://pdbe.org/4i3b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i3b RCSB], [https://www.ebi.ac.uk/pdbsum/4i3b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i3b ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/UNAG_ANGJA UNAG_ANGJA]] Beta-barrel protein that binds unconjugated bilirubin with high affinity. Excitation of the bilirubin-bound protein gives rise to green fluorescence, both under normoxia and hypoxia. The apoprotein is not fluorescent. Does not emit fluorescence in the presence of ditauro-bilirubin, urobilin or biliverdin.<ref>PMID:23768684</ref>
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[https://www.uniprot.org/uniprot/UNAG_ANGJA UNAG_ANGJA] Beta-barrel protein that binds unconjugated bilirubin with high affinity. Excitation of the bilirubin-bound protein gives rise to green fluorescence, both under normoxia and hypoxia. The apoprotein is not fluorescent. Does not emit fluorescence in the presence of ditauro-bilirubin, urobilin or biliverdin.<ref>PMID:23768684</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4i3b" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4i3b" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Green Fluorescent Protein 3D structures|Green Fluorescent Protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Angja]]
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[[Category: Anguilla japonica]]
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[[Category: Ando, R]]
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[[Category: Large Structures]]
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[[Category: Kumagai, A]]
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[[Category: Ando R]]
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[[Category: Miyatake, H]]
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[[Category: Kumagai A]]
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[[Category: Miyawaki, A]]
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[[Category: Miyatake H]]
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[[Category: Beta barrel]]
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[[Category: Miyawaki A]]
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[[Category: Bilirubin binding protein]]
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[[Category: Cytosol]]
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[[Category: Fatty acid binding protein-like]]
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[[Category: Fluorescent protein]]
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[[Category: Lipocalin]]
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Current revision

Crystal structure of fluorescent protein UnaG wild type

PDB ID 4i3b

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