This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4m73

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:41, 8 November 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Mutant structure of methyltransferase from Streptomyces hygroscopicus==
==Mutant structure of methyltransferase from Streptomyces hygroscopicus==
-
<StructureSection load='4m73' size='340' side='right' caption='[[4m73]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
+
<StructureSection load='4m73' size='340' side='right'caption='[[4m73]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4m73]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M73 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M73 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4m73]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_hygroscopicus Streptomyces hygroscopicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M73 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M73 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HF2:(2R)-2-HYDROXY-3-PHENYLPROPANOIC+ACID'>HF2</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=M72:(2R,3R)-2-HYDROXY-3-METHOXY-3-PHENYLPROPANOIC+ACID'>M72</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4kib|4kib]], [[4m6x|4m6x]], [[4m6y|4m6y]], [[4m71|4m71]], [[4m74|4m74]], [[4kic|4kic]], [[4kif|4kif]], [[4kig|4kig]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HF2:(2R)-2-HYDROXY-3-PHENYLPROPANOIC+ACID'>HF2</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=M72:(2R,3R)-2-HYDROXY-3-METHOXY-3-PHENYLPROPANOIC+ACID'>M72</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m73 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m73 OCA], [http://pdbe.org/4m73 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4m73 RCSB], [http://www.ebi.ac.uk/pdbsum/4m73 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4m73 ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m73 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m73 OCA], [https://pdbe.org/4m73 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m73 RCSB], [https://www.ebi.ac.uk/pdbsum/4m73 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m73 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/MPPJ_STRHY MPPJ_STRHY]] S-adenosyl-L-methionine-dependent methyltransferase involved in synthesis of the nonproteinogenic amino acid (2S,3S)-beta-methyl-phenylalanine, a building block of the antibiotic mannopeptimycin.
+
[https://www.uniprot.org/uniprot/MPPJ_STRHY MPPJ_STRHY] S-adenosyl-L-methionine-dependent methyltransferase involved in synthesis of the nonproteinogenic amino acid (2S,3S)-beta-methyl-phenylalanine, a building block of the antibiotic mannopeptimycin.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 19: Line 19:
</div>
</div>
<div class="pdbe-citations 4m73" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4m73" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[SAM-dependent methyltrasferase 3D structures|SAM-dependent methyltrasferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Chan, H C]]
+
[[Category: Large Structures]]
-
[[Category: Huang, C J]]
+
[[Category: Streptomyces hygroscopicus]]
-
[[Category: Li, T L]]
+
[[Category: Chan HC]]
-
[[Category: Liu, Y C]]
+
[[Category: Huang CJ]]
-
[[Category: Zou, X W]]
+
[[Category: Li TL]]
-
[[Category: Methyltransferase]]
+
[[Category: Liu YC]]
-
[[Category: Rossmann fold]]
+
[[Category: Zou XW]]
-
[[Category: Sam/ppy binding]]
+
-
[[Category: Transferase]]
+

Current revision

Mutant structure of methyltransferase from Streptomyces hygroscopicus

PDB ID 4m73

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4m73"
Personal tools