This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4nyn
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
==Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1== | ==Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1== | ||
| - | <StructureSection load='4nyn' size='340' side='right' caption='[[4nyn]], [[Resolution|resolution]] 1.41Å' scene=''> | + | <StructureSection load='4nyn' size='340' side='right'caption='[[4nyn]], [[Resolution|resolution]] 1.41Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4nyn]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4nyn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Halobacterium_salinarum_NRC-1 Halobacterium salinarum NRC-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NYN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NYN FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.41Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | |
| - | <tr id=' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nyn OCA], [https://pdbe.org/4nyn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nyn RCSB], [https://www.ebi.ac.uk/pdbsum/4nyn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nyn ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/RNH_HALSA RNH_HALSA] Nuclease that specifically degrades the RNA of RNA-DNA hybrids; seems to act exonucleolytically on RNA/DNA hybrids. Endonucleolytically removes RNA primers from the Okazaki fragments of lagging strand synthesis on its own. Complements the temperature-sensitive phenotype of an E.coli double rnhA/rnhB (RNase H) disruption mutant.<ref>PMID:15115438</ref> |
==See Also== | ==See Also== | ||
| - | *[[Ribonuclease|Ribonuclease | + | *[[Ribonuclease 3D structures|Ribonuclease 3D structures]] |
| - | + | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Halobacterium salinarum NRC-1]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Angkawidjaja | + | [[Category: Angkawidjaja C]] |
| - | [[Category: Kanaya | + | [[Category: Kanaya S]] |
| - | [[Category: Koga | + | [[Category: Koga Y]] |
| - | [[Category: You | + | [[Category: You DJ]] |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1
| |||||||||||
