This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4pv5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:01, 8 November 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==Crystal structure of mouse glyoxalase I in complexed with 18-beta-glycyrrhetinic acid==
==Crystal structure of mouse glyoxalase I in complexed with 18-beta-glycyrrhetinic acid==
-
<StructureSection load='4pv5' size='340' side='right' caption='[[4pv5]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
+
<StructureSection load='4pv5' size='340' side='right'caption='[[4pv5]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4pv5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PV5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PV5 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4pv5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PV5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PV5 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CBW:(3BETA,5BETA,14BETA)-3-HYDROXY-11-OXOOLEAN-12-EN-29-OIC+ACID'>CBW</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Glo1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CBW:(3BETA,5BETA,14BETA)-3-HYDROXY-11-OXOOLEAN-12-EN-29-OIC+ACID'>CBW</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lactoylglutathione_lyase Lactoylglutathione lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.5 4.4.1.5] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pv5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pv5 OCA], [https://pdbe.org/4pv5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pv5 RCSB], [https://www.ebi.ac.uk/pdbsum/4pv5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pv5 ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pv5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pv5 OCA], [http://pdbe.org/4pv5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pv5 RCSB], [http://www.ebi.ac.uk/pdbsum/4pv5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pv5 ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/LGUL_MOUSE LGUL_MOUSE]] Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B (By similarity).
+
[https://www.uniprot.org/uniprot/LGUL_MOUSE LGUL_MOUSE] Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 20: Line 19:
</div>
</div>
<div class="pdbe-citations 4pv5" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4pv5" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Glyoxalase 3D structures|Glyoxalase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Lactoylglutathione lyase]]
+
[[Category: Large Structures]]
-
[[Category: Lk3 transgenic mice]]
+
[[Category: Mus musculus]]
-
[[Category: Hu, X P]]
+
[[Category: Hu XP]]
-
[[Category: Li, C]]
+
[[Category: Li C]]
-
[[Category: Zhai, J]]
+
[[Category: Zhai J]]
-
[[Category: Zhang, H]]
+
[[Category: Zhang H]]
-
[[Category: Zhang, L P]]
+
[[Category: Zhang LP]]
-
[[Category: Zhao, Y N]]
+
[[Category: Zhao YN]]
-
[[Category: Lyase-lyase inhibitor complex]]
+

Current revision

Crystal structure of mouse glyoxalase I in complexed with 18-beta-glycyrrhetinic acid

PDB ID 4pv5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4pv5"
Personal tools