This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4xj3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:28, 8 November 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Crystal structure of Vibrio cholerae DncV GTP bound form==
==Crystal structure of Vibrio cholerae DncV GTP bound form==
-
<StructureSection load='4xj3' size='340' side='right' caption='[[4xj3]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
+
<StructureSection load='4xj3' size='340' side='right'caption='[[4xj3]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4xj3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XJ3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XJ3 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4xj3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae_O1_biovar_El_Tor_str._N16961 Vibrio cholerae O1 biovar El Tor str. N16961]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XJ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XJ3 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4xj1|4xj1]], [[4xj4|4xj4]], [[4xj5|4xj5]], [[4xj6|4xj6]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xj3 OCA], [http://pdbe.org/4xj3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xj3 RCSB], [http://www.ebi.ac.uk/pdbsum/4xj3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xj3 ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xj3 OCA], [https://pdbe.org/4xj3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xj3 RCSB], [https://www.ebi.ac.uk/pdbsum/4xj3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xj3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/DNCV_VIBCH DNCV_VIBCH]] Catalyzes the synthesis of cyclic AMP-GMP from ATP and GTP. Is also able to produce c-di-AMP and c-di-GMP from ATP and GTP, respectively; however, c-AMP-GMP is the dominant molecule produced by DncV in vivo. Is required for efficient V.cholerae intestinal colonization, and down-regulates the colonization-influencing process of chemotaxis. Is not active with dATP, TTP, UTP, and CTP.
+
[https://www.uniprot.org/uniprot/DNCV_VIBCH DNCV_VIBCH] Catalyzes the synthesis of cyclic AMP-GMP from ATP and GTP. Is also able to produce c-di-AMP and c-di-GMP from ATP and GTP, respectively; however, c-AMP-GMP is the dominant molecule produced by DncV in vivo. Is required for efficient V.cholerae intestinal colonization, and down-regulates the colonization-influencing process of chemotaxis. Is not active with dATP, TTP, UTP, and CTP.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 19: Line 19:
</div>
</div>
<div class="pdbe-citations 4xj3" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4xj3" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Cyclic GMP-AMP synthase 3D synthase|Cyclic GMP-AMP synthase 3D synthase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Ishii, R]]
+
[[Category: Large Structures]]
-
[[Category: Ishitani, R]]
+
[[Category: Vibrio cholerae O1 biovar El Tor str. N16961]]
-
[[Category: Kato, K]]
+
[[Category: Ishii R]]
-
[[Category: Nureki, O]]
+
[[Category: Ishitani R]]
-
[[Category: Bacterial virulence]]
+
[[Category: Kato K]]
-
[[Category: Cyclic gmp-amp synthase]]
+
[[Category: Nureki O]]
-
[[Category: Nucleotidyltransferase]]
+
-
[[Category: Transferase]]
+

Current revision

Crystal structure of Vibrio cholerae DncV GTP bound form

PDB ID 4xj3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4xj3"
Personal tools