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4xn4

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==Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Methionine==
==Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Methionine==
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<StructureSection load='4xn4' size='340' side='right' caption='[[4xn4]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
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<StructureSection load='4xn4' size='340' side='right'caption='[[4xn4]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4xn4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XN4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XN4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4xn4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XN4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XN4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4xms|4xms]], [[4xmt|4xmt]], [[4xmu|4xmu]], [[4xmv|4xmv]], [[4xmw|4xmw]], [[4xmx|4xmx]], [[4xmz|4xmz]], [[4xn1|4xn1]], [[4xn2|4xn2]], [[4xn5|4xn5]], [[4xn7|4xn7]], [[4xn8|4xn8]], [[4xn9|4xn9]], [[4xna|4xna]], [[4xnb|4xnb]], [[4xnd|4xnd]], [[4xo3|4xo3]], [[4xo4|4xo4]], [[4xo5|4xo5]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Membrane_alanyl_aminopeptidase Membrane alanyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.2 3.4.11.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xn4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xn4 OCA], [https://pdbe.org/4xn4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xn4 RCSB], [https://www.ebi.ac.uk/pdbsum/4xn4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xn4 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xn4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xn4 OCA], [http://pdbe.org/4xn4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xn4 RCSB], [http://www.ebi.ac.uk/pdbsum/4xn4 PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/AMPN_ECOLI AMPN_ECOLI]] Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation.
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[https://www.uniprot.org/uniprot/AMPN_ECOLI AMPN_ECOLI] Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation.
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==See Also==
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*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Membrane alanyl aminopeptidase]]
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[[Category: Escherichia coli K-12]]
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[[Category: Addlagatta, A]]
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[[Category: Large Structures]]
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[[Category: Gumpena, R]]
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[[Category: Addlagatta A]]
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[[Category: Hydrolase]]
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[[Category: Gumpena R]]

Current revision

Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Methionine

PDB ID 4xn4

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