This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4zbp

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:43, 8 November 2023) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Crystal structure of the AMPCPR-bound AtNUDT7==
==Crystal structure of the AMPCPR-bound AtNUDT7==
-
<StructureSection load='4zbp' size='340' side='right' caption='[[4zbp]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
+
<StructureSection load='4zbp' size='340' side='right'caption='[[4zbp]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4zbp]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZBP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZBP FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4zbp]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZBP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZBP FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADV:ALPHA-BETA+METHYLENE+ADP-RIBOSE'>ADV</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zb3|4zb3]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADV:ALPHA-BETA+METHYLENE+ADP-RIBOSE'>ADV</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zbp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zbp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4zbp RCSB], [http://www.ebi.ac.uk/pdbsum/4zbp PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zbp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zbp OCA], [https://pdbe.org/4zbp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zbp RCSB], [https://www.ebi.ac.uk/pdbsum/4zbp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zbp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/NUDT7_ARATH NUDT7_ARATH]] Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can use both NADH and ADP-ribose as substrates, but not 8-oxo-dGTP, cyclic ADP-ribose, GDP-manose, UDP-glucose, ATP, or GTP. Exerts negative control of EDS1 signaling.<ref>PMID:15878881</ref> <ref>PMID:16154395</ref> <ref>PMID:16328543</ref> <ref>PMID:16531493</ref> <ref>PMID:17660350</ref>
+
[https://www.uniprot.org/uniprot/NUDT7_ARATH NUDT7_ARATH] Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can use both NADH and ADP-ribose as substrates, but not 8-oxo-dGTP, cyclic ADP-ribose, GDP-manose, UDP-glucose, ATP, or GTP. Exerts negative control of EDS1 signaling.<ref>PMID:15878881</ref> <ref>PMID:16154395</ref> <ref>PMID:16328543</ref> <ref>PMID:16531493</ref> <ref>PMID:17660350</ref>
 +
 
 +
==See Also==
 +
*[[Nudix hydrolase 3D structures|Nudix hydrolase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Ding, J]]
+
[[Category: Arabidopsis thaliana]]
-
[[Category: Liu, C]]
+
[[Category: Large Structures]]
-
[[Category: Tang, Q]]
+
[[Category: Ding J]]
-
[[Category: Zhong, C]]
+
[[Category: Liu C]]
-
[[Category: Ampcpr]]
+
[[Category: Tang Q]]
-
[[Category: Closed conformation]]
+
[[Category: Zhong C]]
-
[[Category: Hydrolase]]
+
-
[[Category: Nudix]]
+

Current revision

Crystal structure of the AMPCPR-bound AtNUDT7

PDB ID 4zbp

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools