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4zby

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<StructureSection load='4zby' size='340' side='right'caption='[[4zby]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='4zby' size='340' side='right'caption='[[4zby]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4zby]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulto Sulto]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZBY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZBY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4zby]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurisphaera_tokodaii_str._7 Sulfurisphaera tokodaii str. 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZBY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZBY FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=URA:URACIL'>URA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zbx|4zbx]], [[4zbz|4zbz]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=URA:URACIL'>URA</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STK_22380 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273063 SULTO])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zby OCA], [https://pdbe.org/4zby PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zby RCSB], [https://www.ebi.ac.uk/pdbsum/4zby PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zby ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Uracil-DNA_glycosylase Uracil-DNA glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.27 3.2.2.27] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zby OCA], [http://pdbe.org/4zby PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zby RCSB], [http://www.ebi.ac.uk/pdbsum/4zby PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zby ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/UDGA_SULTO UDGA_SULTO] Removes uracil bases that are present in DNA as a result of either deamination of cytosine or misincorporation of dUMP instead of dTMP.<ref>PMID:26318717</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Sulto]]
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[[Category: Sulfurisphaera tokodaii str. 7]]
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[[Category: Uracil-DNA glycosylase]]
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[[Category: Kawai A]]
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[[Category: Kawai, A]]
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[[Category: Miyamoto S]]
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[[Category: Miyamoto, S]]
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[[Category: Dna repair]]
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[[Category: Hydrolase]]
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[[Category: Uracil-dna glycosylase]]
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Current revision

Family 4 uracil-DNA glycosylase from Sulfolobus tokodaii (uracil complex form)

PDB ID 4zby

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OCA

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