This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2l2w
From Proteopedia
(Difference between revisions)
| (8 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2l2w.jpg|left|200px]] | ||
| - | + | ==Thiostrepton== | |
| - | + | <StructureSection load='2l2w' size='340' side='right'caption='[[2l2w]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2l2w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_azureus Streptomyces azureus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L2W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L2W FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BB9:(2Z)-2-AMINO-3-SULFANYLPROP-2-ENOIC+ACID'>BB9</scene>, <scene name='pdbligand=DBU:(2Z)-2-AMINOBUT-2-ENOIC+ACID'>DBU</scene>, <scene name='pdbligand=DCY:D-CYSTEINE'>DCY</scene>, <scene name='pdbligand=DHA:2-AMINO-ACRYLIC+ACID'>DHA</scene>, <scene name='pdbligand=MH6:3-HYDROXY-2-IMINOPROPANOIC+ACID'>MH6</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=PRD_000223:THIOSTREPTON'>PRD_000223</scene>, <scene name='pdbligand=QUA:8-HYDROXY-4-(1-HYDROXYETHYL)QUINOLINE-2-CARBOXYLIC+ACID'>QUA</scene>, <scene name='pdbligand=TS9:(2S,3S,4R)-2-AMINO-3,4-DIHYDROXY-3-METHYLPENTANOIC+ACID'>TS9</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l2w OCA], [https://pdbe.org/2l2w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l2w RCSB], [https://www.ebi.ac.uk/pdbsum/2l2w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l2w ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | === | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/THCL_STRAJ THCL_STRAJ] Has bacteriocidal activity. Inhibits bacterial protein biosynthesis by acting on the elongation factor Tu (EF-Tu) (By similarity). | |
| - | + | __TOC__ | |
| - | == | + | </StructureSection> |
| - | [[2l2w]] is a 1 chain structure with sequence from [ | + | [[Category: Large Structures]] |
[[Category: Streptomyces azureus]] | [[Category: Streptomyces azureus]] | ||
| - | [[Category: Arndt | + | [[Category: Arndt H-D]] |
| - | [[Category: Baumann | + | [[Category: Baumann S]] |
| - | [[Category: Hiller | + | [[Category: Hiller F]] |
| - | [[Category: Jonker | + | [[Category: Jonker HRA]] |
| - | [[Category: Kirschner | + | [[Category: Kirschner KN]] |
| - | [[Category: Schoof | + | [[Category: Schoof S]] |
| - | [[Category: Schulte | + | [[Category: Schulte KW]] |
| - | [[Category: Schwalbe | + | [[Category: Schwalbe H]] |
| - | [[Category: Wolf | + | [[Category: Wolf A]] |
Current revision
Thiostrepton
| |||||||||||
Categories: Large Structures | Streptomyces azureus | Arndt H-D | Baumann S | Hiller F | Jonker HRA | Kirschner KN | Schoof S | Schulte KW | Schwalbe H | Wolf A
