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2l2y
From Proteopedia
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| - | {{STRUCTURE_2l2y| PDB=2l2y | SCENE= }} | ||
| - | ===Thiostrepton, epimer form of residue 9=== | ||
| - | == | + | ==Thiostrepton, epimer form of residue 9== |
| - | [[ | + | <StructureSection load='2l2y' size='340' side='right'caption='[[2l2y]]' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[2l2y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_azureus Streptomyces azureus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L2Y FirstGlance]. <br> |
| - | [[2l2y]] is a 1 chain structure with sequence from [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BB9:(2Z)-2-AMINO-3-SULFANYLPROP-2-ENOIC+ACID'>BB9</scene>, <scene name='pdbligand=DBU:(2Z)-2-AMINOBUT-2-ENOIC+ACID'>DBU</scene>, <scene name='pdbligand=DHA:2-AMINO-ACRYLIC+ACID'>DHA</scene>, <scene name='pdbligand=MH6:3-HYDROXY-2-IMINOPROPANOIC+ACID'>MH6</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=PRD_000759:THIOPEPTIDE+THIOSTREPTON+WITH+EPIMER+FORM+OF+RESIDUE+9'>PRD_000759</scene>, <scene name='pdbligand=QUA:8-HYDROXY-4-(1-HYDROXYETHYL)QUINOLINE-2-CARBOXYLIC+ACID'>QUA</scene>, <scene name='pdbligand=TS9:(2S,3S,4R)-2-AMINO-3,4-DIHYDROXY-3-METHYLPENTANOIC+ACID'>TS9</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l2y OCA], [https://pdbe.org/2l2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l2y RCSB], [https://www.ebi.ac.uk/pdbsum/2l2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l2y ProSAT]</span></td></tr> |
| - | < | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/THCL_STRAJ THCL_STRAJ] Has bacteriocidal activity. Inhibits bacterial protein biosynthesis by acting on the elongation factor Tu (EF-Tu) (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Streptomyces azureus]] | [[Category: Streptomyces azureus]] | ||
| - | [[Category: Arndt | + | [[Category: Arndt H-D]] |
| - | [[Category: Baumann | + | [[Category: Baumann S]] |
| - | [[Category: Hiller | + | [[Category: Hiller F]] |
| - | [[Category: Jonker | + | [[Category: Jonker HRA]] |
| - | [[Category: Kirschner | + | [[Category: Kirschner KN]] |
| - | [[Category: Schoof | + | [[Category: Schoof S]] |
| - | [[Category: Schulte | + | [[Category: Schulte KW]] |
| - | [[Category: Schwalbe | + | [[Category: Schwalbe H]] |
| - | [[Category: Wolf | + | [[Category: Wolf A]] |
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Current revision
Thiostrepton, epimer form of residue 9
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Categories: Large Structures | Streptomyces azureus | Arndt H-D | Baumann S | Hiller F | Jonker HRA | Kirschner KN | Schoof S | Schulte KW | Schwalbe H | Wolf A
