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3cwf

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<StructureSection load='3cwf' size='340' side='right'caption='[[3cwf]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='3cwf' size='340' side='right'caption='[[3cwf]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3cwf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacsu Bacsu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CWF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CWF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3cwf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CWF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CWF FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">phoR, BSU29100 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224308 BACSU])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cwf OCA], [https://pdbe.org/3cwf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cwf RCSB], [https://www.ebi.ac.uk/pdbsum/3cwf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cwf ProSAT], [https://www.topsan.org/Proteins/MCSG/3cwf TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cwf OCA], [https://pdbe.org/3cwf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cwf RCSB], [https://www.ebi.ac.uk/pdbsum/3cwf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cwf ProSAT], [https://www.topsan.org/Proteins/MCSG/3cwf TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PHOR_BACSU PHOR_BACSU]] Member of the two-component regulatory system PhoP/PhoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoP in response to environmental signals.
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[https://www.uniprot.org/uniprot/PHOR_BACSU PHOR_BACSU] Member of the two-component regulatory system PhoP/PhoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoP in response to environmental signals.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacsu]]
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[[Category: Bacillus subtilis subsp. subtilis str. 168]]
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[[Category: Histidine kinase]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chang, C]]
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[[Category: Chang C]]
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[[Category: Gu, M]]
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[[Category: Gu M]]
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[[Category: Joachimiak, A]]
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[[Category: Joachimiak A]]
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[[Category: Structural genomic]]
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[[Category: Tesar C]]
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[[Category: Tesar, C]]
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[[Category: Alkaline phosphatase synthesis sensor protein phor]]
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[[Category: Bacillus subtili]]
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[[Category: Kinase]]
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[[Category: Mcsg]]
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[[Category: Membrane]]
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[[Category: Pas domain]]
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[[Category: Phosphate transport]]
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[[Category: Phosphoprotein]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Transferase]]
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[[Category: Transmembrane]]
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[[Category: Transport]]
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[[Category: Two-component regulatory system]]
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Revision as of 17:29, 8 November 2023

Crystal structure of PAS domain of two-component sensor histidine kinase

PDB ID 3cwf

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