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5mpg
From Proteopedia
(Difference between revisions)
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==Solution NMR structure of hnRNP A1 RRM1 in complex with 5'-UUAGGUC-3' RNA== | ==Solution NMR structure of hnRNP A1 RRM1 in complex with 5'-UUAGGUC-3' RNA== | ||
| - | <StructureSection load='5mpg' size='340' side='right'caption='[[5mpg | + | <StructureSection load='5mpg' size='340' side='right'caption='[[5mpg]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5mpg]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5mpg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MPG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MPG FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mpg OCA], [https://pdbe.org/5mpg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mpg RCSB], [https://www.ebi.ac.uk/pdbsum/5mpg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mpg ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Disease == | == Disease == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/ROA1_HUMAN ROA1_HUMAN] Amyotrophic lateral sclerosis;Inclusion body myopathy with Paget disease of bone and frontotemporal dementia. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref> The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref> |
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/ROA1_HUMAN ROA1_HUMAN] Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May play a role in HCV RNA replication.<ref>PMID:17229681</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Allain | + | [[Category: Allain FH-T]] |
| - | [[Category: Barraud | + | [[Category: Barraud P]] |
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Current revision
Solution NMR structure of hnRNP A1 RRM1 in complex with 5'-UUAGGUC-3' RNA
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