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5mxk

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Current revision (17:53, 8 November 2023) (edit) (undo)
 
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<StructureSection load='5mxk' size='340' side='right'caption='[[5mxk]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
<StructureSection load='5mxk' size='340' side='right'caption='[[5mxk]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5mxk]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MXK OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5MXK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5mxk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MXK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MXK FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZHA:~{N}-(5-oxidanylidene-7,8-dihydro-6~{H}-naphthalen-2-yl)ethanamide'>ZHA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.932&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5mxk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mxk OCA], [http://pdbe.org/5mxk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mxk RCSB], [http://www.ebi.ac.uk/pdbsum/5mxk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mxk ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZHA:~{N}-(5-oxidanylidene-7,8-dihydro-6~{H}-naphthalen-2-yl)ethanamide'>ZHA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mxk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mxk OCA], [https://pdbe.org/5mxk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mxk RCSB], [https://www.ebi.ac.uk/pdbsum/5mxk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mxk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU]] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref>
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[https://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5mxk" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5mxk" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Abell, C]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Blundell, T L]]
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[[Category: Abell C]]
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[[Category: Chan, D S.H]]
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[[Category: Blundell TL]]
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[[Category: Coyne, A G]]
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[[Category: Chan DS-H]]
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[[Category: Matak-Vinkovic, D]]
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[[Category: Coyne AG]]
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[[Category: McConnell, B]]
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[[Category: Matak-Vinkovic D]]
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[[Category: Mendes, V]]
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[[Category: McConnell B]]
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[[Category: Thomas, S E]]
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[[Category: Mendes V]]
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[[Category: Ethr]]
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[[Category: Thomas SE]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Repressor]]
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[[Category: Tetr]]
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[[Category: Transcription]]
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Current revision

Structure of Mycobacterium Tuberculosis Transcriptional Regulatory Repressor Protein (EthR) in complex with fragment 7G9.

PDB ID 5mxk

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