This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5n5n

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (18:03, 8 November 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Cryo-EM structure of tsA201 cell alpha1B and betaI and betaIVb microtubules==
==Cryo-EM structure of tsA201 cell alpha1B and betaI and betaIVb microtubules==
-
<StructureSection load='5n5n' size='340' side='right'caption='[[5n5n]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
+
<SX load='5n5n' size='340' side='right' viewer='molstar' caption='[[5n5n]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5n5n]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N5N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5N5N FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5n5n]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N5N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5N5N FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=G2P:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>G2P</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TUBB, TUBB5, OK/SW-cl.56 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), TUBA1B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G2P:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>G2P</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5n5n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n5n OCA], [http://pdbe.org/5n5n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5n5n RCSB], [http://www.ebi.ac.uk/pdbsum/5n5n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5n5n ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5n5n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n5n OCA], [https://pdbe.org/5n5n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5n5n RCSB], [https://www.ebi.ac.uk/pdbsum/5n5n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5n5n ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/TBB5_HUMAN TBB5_HUMAN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/TBA1B_HUMAN TBA1B_HUMAN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
+
[https://www.uniprot.org/uniprot/TBB5_HUMAN TBB5_HUMAN] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 19: Line 19:
</div>
</div>
<div class="pdbe-citations 5n5n" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5n5n" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Tubulin 3D Structures|Tubulin 3D Structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
-
</StructureSection>
+
</SX>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Atherton, J]]
+
[[Category: Atherton J]]
-
[[Category: Moores, C A]]
+
[[Category: Moores CA]]
-
[[Category: Roll-Mecak, A]]
+
[[Category: Roll-Mecak A]]
-
[[Category: Spector, J O]]
+
[[Category: Spector JO]]
-
[[Category: Vemu, A]]
+
[[Category: Vemu A]]
-
[[Category: Microtubules dynamics tubulin isoform]]
+
-
[[Category: Structural protein]]
+

Current revision

Cryo-EM structure of tsA201 cell alpha1B and betaI and betaIVb microtubules

5n5n, resolution 4.00Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5n5n"
Personal tools