This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1evc

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:49, 15 November 2023) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1evc.jpg|left|200px]]
 
-
{{Structure
+
==NMR structure of CYANOBACTERIAL TOXIN, PHOSPHATASE-1/-2A INHIBITOR==
-
|PDB= 1evc |SIZE=350|CAPTION= <scene name='initialview01'>1evc</scene>
+
<StructureSection load='1evc' size='340' side='right'caption='[[1evc]]' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=ACB:3-METHYL-ASPARTIC+ACID'>ACB</scene>, <scene name='pdbligand=ADD:2,6,8-TRIMETHYL-3-AMINO-9-BENZYL-9-METHOXYNONANOIC+ACID'>ADD</scene>, <scene name='pdbligand=ILG:GLUTAMYL+GROUP'>ILG</scene>, <scene name='pdbligand=MDH:N-METHYLDEHYDROBUTYRINE'>MDH</scene>
+
<table><tr><td colspan='2'>[[1evc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Unidentified Unidentified]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EVC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EVC FirstGlance]. <br>
-
|ACTIVITY=
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
|GENE=
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1ZN:(2S,3S,4E,6E,8S,9S)-3-AMINO-9-METHOXY-2,6,8-TRIMETHYL-10-PHENYLDECA-4,6-DIENOIC+ACID'>1ZN</scene>, <scene name='pdbligand=ACB:3-METHYL-BETA-D-ASPARTIC+ACID'>ACB</scene>, <scene name='pdbligand=FGA:GAMMA-D-GLUTAMIC+ACID'>FGA</scene>, <scene name='pdbligand=MDH:N-METHYLDEHYDROBUTYRINE'>MDH</scene>, <scene name='pdbligand=PRD_000213:motuporin'>PRD_000213</scene></td></tr>
-
|DOMAIN=
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1evc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1evc OCA], [https://pdbe.org/1evc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1evc RCSB], [https://www.ebi.ac.uk/pdbsum/1evc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1evc ProSAT]</span></td></tr>
-
|RELATEDENTRY=[[1evd|1EVD]]
+
</table>
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1evc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1evc OCA], [http://www.ebi.ac.uk/pdbsum/1evc PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1evc RCSB]</span>
+
<div style="background-color:#fffaf0;">
-
}}
+
== Publication Abstract from PubMed ==
-
 
+
-
'''CYANOBACTERIAL TOXIN, PHOSPHATASE-1/-2A INHIBITOR, NMR'''
+
-
 
+
-
 
+
-
==Overview==
+
A comparison of the structures of two cyanobacterial toxins yields insights into how they may inhibit protein phosphatase-1 and -2A and why microcystins but not motuporin may covalently modify their protein phosphatase targets.
A comparison of the structures of two cyanobacterial toxins yields insights into how they may inhibit protein phosphatase-1 and -2A and why microcystins but not motuporin may covalently modify their protein phosphatase targets.
-
==About this Structure==
+
Comparison of the solution structures of microcystin-LR and motuporin.,Bagu JR, Sonnichsen FD, Williams D, Andersen RJ, Sykes BD, Holmes CF Nat Struct Biol. 1995 Feb;2(2):114-6. PMID:7749913<ref>PMID:7749913</ref>
-
1EVC is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Producing_organism_not_known Producing organism not known]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EVC OCA].
+
-
 
+
-
==Reference==
+
-
Comparison of the solution structures of microcystin-LR and motuporin., Bagu JR, Sonnichsen FD, Williams D, Andersen RJ, Sykes BD, Holmes CF, Nat Struct Biol. 1995 Feb;2(2):114-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7749913 7749913]
+
-
[[Category: Producing organism not known]]
+
-
[[Category: Protein complex]]
+
-
[[Category: Bagu, J R.]]
+
-
[[Category: Sykes, B D.]]
+
-
[[Category: cyanobacterial toxin]]
+
-
[[Category: phosphatase-1/-2a inhibitor]]
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:10:22 2008''
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 +
</div>
 +
<div class="pdbe-citations 1evc" style="background-color:#fffaf0;"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Unidentified]]
 +
[[Category: Bagu JR]]
 +
[[Category: Sykes BD]]

Current revision

NMR structure of CYANOBACTERIAL TOXIN, PHOSPHATASE-1/-2A INHIBITOR

PDB ID 1evc

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools