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1jen

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==HUMAN S-ADENOSYLMETHIONINE DECARBOXYLASE==
==HUMAN S-ADENOSYLMETHIONINE DECARBOXYLASE==
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<StructureSection load='1jen' size='340' side='right' caption='[[1jen]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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<StructureSection load='1jen' size='340' side='right'caption='[[1jen]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1jen]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JEN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JEN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1jen]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JEN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JEN FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosylmethionine_decarboxylase Adenosylmethionine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.50 4.1.1.50] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jen OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jen RCSB], [http://www.ebi.ac.uk/pdbsum/1jen PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jen OCA], [https://pdbe.org/1jen PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jen RCSB], [https://www.ebi.ac.uk/pdbsum/1jen PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jen ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DCAM_HUMAN DCAM_HUMAN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/je/1jen_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/je/1jen_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jen ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1jen" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Adenosylmethionine decarboxylase]]
 
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Ealick, S E.]]
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[[Category: Large Structures]]
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[[Category: Ekstrom, J L.]]
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[[Category: Ealick SE]]
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[[Category: Mathews, I I.]]
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[[Category: Ekstrom JL]]
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[[Category: Pegg, A E.]]
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[[Category: Mathews II]]
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[[Category: Stanley, B A.]]
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[[Category: Pegg AE]]
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[[Category: Allosteric enzyme]]
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[[Category: Stanley BA]]
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[[Category: Gene duplication]]
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[[Category: Polyamine biosynthesis]]
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[[Category: Pyruvoyl]]
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[[Category: S-adenosylmethionine decarboxylase]]
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[[Category: Sandwich]]
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Current revision

HUMAN S-ADENOSYLMETHIONINE DECARBOXYLASE

PDB ID 1jen

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