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Sequestosome

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Current revision (08:28, 15 November 2023) (edit) (undo)
 
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[[6mj7]] – hSQS-1 ZZ domain + Arg<br />
[[6mj7]] – hSQS-1 ZZ domain + Arg<br />
[[6khz]] – hSQS-1 ZZ domain + Gly<br />
[[6khz]] – hSQS-1 ZZ domain + Gly<br />
 +
[[7r1o]] – hSQS-1 ZZ domain + drug<br />
[[2ktr]] – rSQS PB1 domain – rat - NMR<br />
[[2ktr]] – rSQS PB1 domain – rat - NMR<br />
[[2kkc]] – rSQS PB1 domain (mutant) - NMR<br />
[[2kkc]] – rSQS PB1 domain (mutant) - NMR<br />

Current revision

Structure of human sequestosome UBA domain (PDB code 2jy8)

Drag the structure with the mouse to rotate

References

  1. Seibenhener ML, Babu JR, Geetha T, Wong HC, Krishna NR, Wooten MW. Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation. Mol Cell Biol. 2004 Sep;24(18):8055-68. PMID:15340068 doi:10.1128/MCB.24.18.8055-8068.2004
  2. Salminen A, Kaarniranta K, Haapasalo A, Hiltunen M, Soininen H, Alafuzoff I. Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease. Prog Neurobiol. 2012 Jan;96(1):87-95. doi: 10.1016/j.pneurobio.2011.11.005. Epub , 2011 Nov 22. PMID:22138392 doi:http://dx.doi.org/10.1016/j.pneurobio.2011.11.005

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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