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2omk

From Proteopedia

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[[Image:2omk.gif|left|200px]]
 
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{{Structure
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==Structure of the Bacteroides Thetaiotaomicron Thiamin Pyrophosphokinase==
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|PDB= 2omk |SIZE=350|CAPTION= <scene name='initialview01'>2omk</scene>, resolution 1.80&Aring;
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<StructureSection load='2omk' size='340' side='right'caption='[[2omk]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=SNN:L-3-AMINOSUCCINIMIDE'>SNN</scene>
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<table><tr><td colspan='2'>[[2omk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron_VPI-5482 Bacteroides thetaiotaomicron VPI-5482]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OMK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OMK FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thiamine_diphosphokinase Thiamine diphosphokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.6.2 2.7.6.2] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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|GENE= BT2397 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=818 Bacteroides thetaiotaomicron])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=SNN:L-3-AMINOSUCCINIMIDE'>SNN</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1564 THI80], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam04263 TPK_catalytic]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2omk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2omk OCA], [https://pdbe.org/2omk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2omk RCSB], [https://www.ebi.ac.uk/pdbsum/2omk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2omk ProSAT], [https://www.topsan.org/Proteins/MCSG/2omk TOPSAN]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2omk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2omk OCA], [http://www.ebi.ac.uk/pdbsum/2omk PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2omk RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/Q8A545_BACTN Q8A545_BACTN]
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== Evolutionary Conservation ==
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'''Structure of the Bacteroides Thetaiotaomicron Thiamin Pyrophosphokinase'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/om/2omk_consurf.spt"</scriptWhenChecked>
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2OMK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OMK OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Bacteroides thetaiotaomicron]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Single protein]]
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</jmolCheckbox>
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[[Category: Thiamine diphosphokinase]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2omk ConSurf].
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[[Category: Abdullah, J.]]
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<div style="clear:both"></div>
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[[Category: Anderson, W F.]]
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__TOC__
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[[Category: Collart, F R.]]
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</StructureSection>
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[[Category: Joachimiak, A.]]
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[[Category: Bacteroides thetaiotaomicron VPI-5482]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Large Structures]]
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[[Category: Minasov, G.]]
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[[Category: Abdullah J]]
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[[Category: Shuvalova, L.]]
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[[Category: Anderson WF]]
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[[Category: Vorontsov, I I.]]
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[[Category: Collart FR]]
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[[Category: crystal structure]]
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[[Category: Joachimiak A]]
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[[Category: mcsg]]
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[[Category: Minasov G]]
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[[Category: midwest center for structural genomic]]
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[[Category: Shuvalova L]]
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[[Category: protein structure initiative]]
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[[Category: Vorontsov II]]
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[[Category: psi-2]]
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[[Category: structural genomic]]
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[[Category: succinimide]]
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[[Category: thiamin pyrophosphokinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:19:59 2008''
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Current revision

Structure of the Bacteroides Thetaiotaomicron Thiamin Pyrophosphokinase

PDB ID 2omk

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